Target Name: PGLYRP3
NCBI ID: G114771
Review Report on PGLYRP3 Target / Biomarker Content of Review Report on PGLYRP3 Target / Biomarker
PGLYRP3
Other Name(s): peptidoglycan recognition protein 3 | Peptidoglycan recognition protein intermediate alpha | PGRP3_HUMAN | peptidoglycan recognition protein intermediate alpha | PGRP-Ialpha | PGLYRPIalpha | Peptidoglycan recognition protein I alpha | Peptidoglycan recognition protein I-alpha | PGRP-I-alpha | Peptidoglycan recognition protein-I-alpha | PGRPIA | Peptidoglycan recognition protein 3 | MGC149197 | peptidoglycan recognition protein I alpha

PGLYRP3: A Potential Drug Target and Biomarker for the Treatment of various diseases

Introduction

PGLYRP3 (Peptidoglycan Recognition Protein 3) is a protein that is expressed in various cell types of the human body. It is a member of the glycoprotein family, which consists of proteins that are involved in cell signaling, tissue repair, and inflammation. PGLYRP3 is a 21-kDa protein that is expressed in the liver, spleen, and pancreas. Its function is to recognize and interact with various peptidoglycans, which are a type of protein that is derived from the linker between the amino acids that make up a glycoprotein.

PGLYRP3 is a key regulator of the linker between the amino acids that make up a glycoprotein. It plays a critical role in the regulation of cell signaling, as it helps to ensure that properly sized and interacting peptidoglycans are introduced into the cytosol. It also helps to ensure that the linker between the amino acids that make up a glycoprotein is stable and resistant to degradation.

PGLYRP3 is also involved in the regulation of tissue repair and inflammation. It helps to ensure that the cytosol is properly equipped to support the repair of damaged tissue and that the immune system is able to respond to an infection.

PGLYRP3 is a potential drug target, as it can be targeted with small molecules and antibodies. Studies have shown that PGLYRP3 is highly targeted, with several studies reporting that inhibition of PGLYRP3 has led to the downregulation of its downstream targets. PGLYRP3 has also been shown to be a potential biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

PGLYRP3 as a Drug Target

PGLYRP3 is an attractive drug target due to its diverse functions and its involvement in multiple cellular processes. One of the main targets of PGLYRP3 is the regulation of cell signaling. It is well known that PGLYRP3 plays a critical role in the regulation of cell signaling by ensuring that the cytosol is properly equipped to support the delivery of signals from the cell surface to the cytosol.

PGLYRP3 has been shown to play a critical role in the regulation of several cellular signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. TGF-β is a cytokine that plays a critical role in cell signaling, and it is well known that PGLYRP3 is involved in its regulation. Studies have shown that PGLYRP3 inhibition has led to the downregulation of TGF-β signaling, which can lead to the inhibition of cell growth, apoptosis, and other cellular processes.

Another potential drug target for PGLYRP3 is the regulation of inflammation. PGLYRP3 is involved in the regulation of inflammation by ensuring that the cytosol is properly equipped to support the delivery of immune cells to the site of inflammation. Studies have shown that PGLYRP3 inhibition has led to the inhibition of the immune response, which can lead to the inhibition of tissue repair and the progression of inflammation.

PGLYRP3 as a Biomarker

PGLYRP3 is also an attractive biomarker for a variety of diseases due to its involvement in the regulation of multiple cellular processes. Studies have shown that PGLYRP3 is involved in the regulation of a wide range of cellular processes, including cell signaling, tissue repair, and inflammation . As such, PGLYRP3 has been shown to be a potential biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

PGLYRP3 is involved in the regulation of

Protein Name: Peptidoglycan Recognition Protein 3

Functions: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity

The "PGLYRP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PGLYRP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PGLYRP4 | PGM1 | PGM2 | PGM2L1 | PGM3 | PGM5 | PGM5-AS1 | PGM5P2 | PGM5P4 | PGM5P4-AS1 | PGP | PGPEP1 | PGPEP1L | PGR | PGR-AS1 | PGRMC1 | PGRMC2 | PGS1 | PHACTR1 | PHACTR2 | PHACTR3 | PHACTR3-AS1 | PHACTR4 | PHAF1 | PHAX | PHB1 | PHB1P1 | PHB1P19 | PHB1P3 | PHB1P8 | PHB1P9 | PHB2 | PHC1 | PHC1P1 | PHC2 | PHC2-AS1 | PHC3 | Phenylalanyl-tRNA synthetase | PHETA1 | PHETA2 | PHEX | PHEX-AS1 | PHF1 | PHF10 | PHF11 | PHF12 | PHF13 | PHF14 | PHF19 | PHF2 | PHF2-ARID5B complex | PHF20 | PHF20L1 | PHF21A | PHF21B | PHF23 | PHF24 | PHF2P1 | PHF2P2 | PHF3 | PHF5A | PHF6 | PHF7 | PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A