Target Name: PHACTR1
NCBI ID: G221692
Review Report on PHACTR1 Target / Biomarker Content of Review Report on PHACTR1 Target / Biomarker
PHACTR1
Other Name(s): Phosphatase and actin regulator 1 (isoform a) | PHACTR1 variant 1 | Phosphatase and actin regulator 1, transcript variant 2 | EIEE70 | MGC126575 | dJ257A7.2 | DEE70 | RPEL1 | phosphatase and actin regulator 1 | PHACTR1 variant 2 | PHAR1_HUMAN | MGC126577 | Phosphatase and actin regulator 1, transcript variant 1 | RPEL repeat containing 1 | Phosphatase and actin regulator 1 | RPEL | KIAA1733

PHACTR1: A Protein Regulating Cellular Processes

PHACTR1, also known as phosphatase and actin regulator 1 (isoform a), is a protein that is expressed in various tissues and organs throughout the body. It plays a crucial role in the regulation of cellular processes that are essential for cell survival, such as cell signaling, DNA replication, and protein synthesis.

PHACTR1 is a member of the actin regulatory protein family, which includes proteins that regulate actin filament formation and dynamics. These proteins are involved in the regulation of various cellular processes that are critical for cell survival, such as the movement of cells, the formation of tissues, and the regulation of cell signaling pathways.

PHACTR1 is a 21-kDa protein that is expressed in various tissues and organs, including muscle, heart, liver, and brain. It is highly conserved, with a calculated pI of 6.9 and a predicted localization in the cytoplasm. PHACTR1 is also known to be a potent inhibitor of the protein kinase A, which is involved in various cellular processes that are critical for cell survival.

PHACTR1 has been shown to play a role in the regulation of cellular signaling pathways that are critical for cell survival. For example, studies have shown that PHACTR1 is involved in the regulation of the signal transduction pathway, which is involved in the regulation of cellular processes that are critical for cell survival.

Additionally, PHACTR1 has been shown to play a role in the regulation of DNA replication, which is a critical process for the regulation of cell growth and division. Studies have shown that PHACTR1 is involved in the regulation of DNA replication, and that its activity is regulated by various factors, such as the concentration of DNA replication factors and the activity of DNA polymerases.

PHACTR1 has also been shown to play a role in the regulation of protein synthesis, which is a critical process for the regulation of cellular processes that are essential for cell survival. Studies have shown that PHACTR1 is involved in the regulation of protein synthesis, and that Its activity is regulated by various factors, such as the concentration of protein synthesis factors and the activity of protein synthesizing enzymes.

In conclusion, PHACTR1 is a protein that is involved in the regulation of various cellular processes that are critical for cell survival. Its activity is regulated by various factors, including the concentration of DNA replication factors, the activity of DNA polymerases, and the activity of protein synthesis factors. As a result, PHACTR1 may be a drug target or biomarker for various diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

Protein Name: Phosphatase And Actin Regulator 1

Functions: Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (PubMed:21798305, PubMed:21939755). Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity)

The "PHACTR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHACTR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHACTR2 | PHACTR3 | PHACTR3-AS1 | PHACTR4 | PHAF1 | PHAX | PHB1 | PHB1P1 | PHB1P19 | PHB1P3 | PHB1P8 | PHB1P9 | PHB2 | PHC1 | PHC1P1 | PHC2 | PHC2-AS1 | PHC3 | Phenylalanyl-tRNA synthetase | PHETA1 | PHETA2 | PHEX | PHEX-AS1 | PHF1 | PHF10 | PHF11 | PHF12 | PHF13 | PHF14 | PHF19 | PHF2 | PHF2-ARID5B complex | PHF20 | PHF20L1 | PHF21A | PHF21B | PHF23 | PHF24 | PHF2P1 | PHF2P2 | PHF3 | PHF5A | PHF6 | PHF7 | PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16