PHACTR4: A Potential Drug Target and Biomarker (G65979)

Target Name: PHACTR4

NCBI ID: G65979

PHACTR4

PHACTR4: A Potential Drug Target and Biomarker

PHACTR4, also known as PHACTR4 variant 1, is a gene that encodes a protein involved in the regulation of actinin, a protein that is found in the actin filaments of cells. PHACTR4 is a member of the PHACTR gene family, which is known for its role in the regulation of actinin. In recent years, researchers have become increasingly interested in the study of PHACTR4 and its potential as a drug target and biomarker.

The actin filaments of cells are made up of a protein called actinin, which helps to regulate the movement of cells. PHACTR4 is a protein that is involved in the regulation of actinin. It is made up of 1,212 amino acids and has a molecular weight of 17.9 kDa. PHACTR4 is expressed in a variety of tissues, including muscle, heart, and brain.

One of the key functions of PHACTR4 is its role in regulating the level of actinin in the actin filaments. Actinin is a protein that is involved in the regulation of cell growth, and it helps to keep the cell organized. By regulating the level of actinin, PHACTR4 helps to ensure that the cell grows and functions properly.

PHACTR4 is also involved in the regulation of the stability of the actin filaments. Actinin helps to keep the actin filaments stable, which is important for the proper movement of cells. If the actin filaments are not stable, cells can become disorganized and may undergo apoptosis, a process that is associated with the death of cells.

In addition to its role in regulating actinin, PHACTR4 is also involved in the regulation of other proteins. It is a component of the protein complex that is responsible for regulating the level of actinin in the actin filaments. It is also a component of the protein complex that is responsible for regulating the stability of the actin filaments.

PHACTR4 is a gene that is known as a potential drug target. Its involvement in the regulation of actinin and its role in the regulation of other proteins make it an attractive target for drug developers. Researchers have been studying the PHACTR4 gene for years in order to understand its role in the regulation of actinin and its potential as a drug target.

In addition to its potential as a drug target, PHACTR4 is also a potential biomarker. Its involvement in the regulation of actinin and its role in the regulation of other proteins make it an attractive candidate for use as a biomarker for a variety of diseases. For example, PHACTR4 levels may be elevated in certain diseases, such as cancer, and could be used as a biomarker to monitor the effectiveness of certain treatments.

Overall, PHACTR4 is a gene that is involved in the regulation of actinin and its potential as a drug target and biomarker make it an attractive target for further research. Further studies are needed to fully understand its role in the regulation of actinin and its potential as a drug and biomarker.

Protein Name: Phosphatase And Actin Regulator 4

Functions: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway (By similarity)

The "PHACTR4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHACTR4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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