NEO1: A Protein Involved in Immune Regulation and Cell Adhesion

Target Name: NEO1

NCBI ID: G4756

NEO1

NEO1: A Protein Involved in Immune Regulation and Cell Adhesion

NEO1 (Immunoglobulin superfamily DCC subclass member 2) is a protein that is expressed in various tissues throughout the body, including the brain, spleen, heart, kidneys, and intestine. It is a member of the immunoglobulin superfamily, which is a large family of proteins that are involved in the immune response.

One of the functions of NEO1 is to help regulate the immune response. It is part of a subclass of proteins called the DCC (doublecortin-containing) subclass, which are characterized by the presence of a doublecortin repeat in their extracellular domain. This repeat is known for its ability to interact with other proteins and to regulate their activity.

NEO1 has been shown to play a role in the regulation of inflammation and autoimmune diseases. It has been shown to regulate the activity of immune cells, including T cells and B cells, and to help control the production of antibodies. It has also been shown to play a role in the regulation of inflammation, both in the context of normal immune responses and in the context of autoimmune diseases.

In addition to its role in immune regulation, NEO1 has also been shown to have other functions. It is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. It is also involved in the regulation of cell survival, and in the regulation of cell proliferation.

Given its involvement in both immune regulation and cell adhesion, NEO1 is a potential drug target. Researchers are currently working to develop compounds that can inhibit the activity of NEO1 and use it as a therapeutic agent in a variety of diseases, including autoimmune diseases and cancer. These compounds may be used to treat a wide range of conditions, including rheumatoid arthritis, lupus, and multiple sclerosis.

Overall, NEO1 is a protein that has important functions in both immune regulation and cell adhesion. As a result, it is a promising target for the development of new drugs for a variety of diseases. Further research is needed to fully understand the role of NEO1 in the immune system and its potential as a drug.

Protein Name: Neogenin 1

Functions: Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response

The "NEO1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NEO1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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