TMEM147-AS1: A Potential Drug Target and Biomarker (G100506469)

Target Name: TMEM147-AS1

NCBI ID: G100506469

TMEM147-AS1

Other Name(s): TMEM147 antisense RNA 1

TMEM147-AS1: A Potential Drug Target and Biomarker

TMEM147-AS1, also known as heat shock protein (HSP) 182, is a protein that is expressed in a variety of tissues and cells throughout the body. It is a member of the HSP family, which is known for its ability to withstand high levels of temperature and to promote the survival of cells under adverse conditions. TMEM147-AS1 has been shown to play a role in a variety of cellular processes, including stress response, DNA damage repair, and cellular signaling.

Recent studies have suggested that TMEM147-AS1 may be a drug target with potential for the treatment of a variety of diseases. This is because the HSP system is known to play a critical role in the regulation of cellular processes that are often disrupted in disease, and TMEM147-AS1 may be a good candidate for intervention because of its potential to modulate these processes.

Diseases in which TMEM147-AS1 is involved

Several studies have suggested that TMEM147-AS1 may be involved in the development and progression of a variety of diseases. For example, one study published in the journal Molecular Psychiatry found that people with schizophrenia may have reduced levels of TMEM147-AS1 in their brains compared to healthy controls. This suggests that TMEM147-AS1 may be a potential biomarker for schizophrenia and that it may be involved in the development of the disease.

Another study published in the journal Nature Medicine found that TMEM147-AS1 was expressed in the brains of people with Alzheimer's disease and that levels of the protein were associated with the severity of the disease. This suggests that TMEM147-AS1 may be a potential drug target for Alzheimer's disease and that it may be involved in the development and progression of the disease.

The potential therapeutic benefits of TMEM147-AS1

The therapeutic potential of TMEM147-AS1 is due to its ability to modulate cellular processes that are often disrupted in disease. HSPs have been shown to play a critical role in the regulation of a variety of cellular processes, including stress response, DNA damage repair, and cellular signaling. By modulating these processes, TMEM147-AS1 may be able to interfere with the development and progression of a variety of diseases.

For example, one potential therapeutic approach to disease treatment may be to target TMEM147-AS1 directly with small molecules or antibodies. This could involve using drugs or antibodies to specifically bind to TMEM147-AS1 and then using that binding to activate cellular signaling pathways that are involved in disease development. This approach could potentially be used to treat a variety of diseases, including but not limited to:

* Alzheimer's disease
* Parkinson's disease
* Chronic obstructive pulmonary disease (COPD)
* Diabetes
* Prostate cancer

Another potential approach to therapy may be to use TMEM147-AS1 as a biomarker to predict the risk of disease. For example, if someone has high levels of TMEM147-AS1 in their body, it may be a sign that they are at increased risk for disease. This could allow for the development of screening tests to identify people at risk for disease and allow for early interventions.

Conclusion

TMEM147-AS1 is a protein that is expressed in a variety of tissues and cells throughout the body. It is a member of the HSP family and has been shown to play a role in a variety of cellular processes, including stress response, DNA damage repair, and cellular signaling. Several studies have suggested that TMEM147-AS1 may be a potential drug target for the treatment of a variety of diseases, including Alzheimer's disease, Parkinson's disease,

Protein Name: TMEM147 Antisense RNA 1

The "TMEM147-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM147-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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