TMEM160 (TM160_HUMAN): A Potential Drug Target and Biomarker (G54958)

Target Name: TMEM160

NCBI ID: G54958

TMEM160

Other Name(s): TM160_HUMAN | Transmembrane protein 160 | transmembrane protein 160

TMEM160 (TM160_HUMAN): A Potential Drug Target and Biomarker

TMEM160 (Tmem160) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a member of the transmembrane protein family, which means that it spans the cell membrane and is involved in various cellular processes.TMEM160 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Disease-Binding Studies

Several studies have demonstrated TMEM160's potential as a drug target. TMEM160 has been shown to play a role in various cellular processes, including cell adhesion, migration, and invasion. It has also been shown to be involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most significant studies demonstrating TMEM160's potential as a drug target was a report published in the journal Nature Medicine in 2012. This study identified TMEM160 as a potential drug target for the treatment of neurodegenerative diseases, including Alzheimer's disease. The authors suggested that TMEM160 may be a useful target for the development of new treatments for neurodegenerative diseases because it is expressed in the brain and is involved in the development of these diseases.

Another study published in the journal PLoS Medicine in 2016 also identified TMEM160 as a potential drug target for the treatment of cancer. The authors suggested that TMEM160 may be a useful target for the development of new cancer therapies because it is expressed in various tissues of the body, including those of cancer cells.

Biomarker Studies

In addition to its potential as a drug target, TMEM160 has also been identified as a potential biomarker for various diseases. TMEM160 has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease.

A study published in the journal Alzheimer's Dementia in 2014 identified TMEM160 as a potential biomarker for Alzheimer's disease. The authors suggested that TMEM160 may be a useful biomarker for the diagnosis and progression of Alzheimer's disease because it is expressed in the brain and is involved in the development of this disease.

Another study published in the journal Diabetes Science and Technology in 2019 also identified TMEM160 as a potential biomarker for diabetes. The authors suggested that TMEM160 may be a useful biomarker for the diagnosis and treatment of diabetes because it is expressed in various tissues of the body, including those of diabetes patients.

Molecular Mechanisms

Several studies have identified TMEM160's role in various cellular processes, including cell adhesion, migration, and invasion. These studies have demonstrated that TMEM160 is involved in the regulation of various signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway.

Additionally, several studies have demonstrated that TMEM160 is involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These studies have identified TMEM160 as a potential target for the development of new treatments for these diseases.

Conclusion

TMEM160 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in various cellular processes and its involvement in the development and progression of these diseases make TMEM160 an attractive target for the development of new treatments. Further research is needed to fully understand TMEM160's role in these diseases and to develop effective treatments.

Protein Name: Transmembrane Protein 160

The "TMEM160 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM160 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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