Target Name: PLG
NCBI ID: G5340
Review Report on PLG Target / Biomarker Content of Review Report on PLG Target / Biomarker
PLG
Other Name(s): HAE4 | Plasmin | PLMN_HUMAN | AS4.5 | plasminogen | Actase | Plasminogen precursor | Plasmin heavy chain A, short form | Plasminogen, transcript variant 1 | Angiostatin | plasmin | Plasmin light chain B | Plasminogen (isoform 1) | Serum tryptase | Activation peptide | Angiostatin_(HUMAN) | Plasmin_(HUMAN) | Plasmin (Human) | Fibrinolysin | Plasmin heavy chain A | Angiostatin (Human) | Fibrinase | Plasminogen | Thrombolysin | PLG variant 1

PLG: A Drug Target / Disease Biomarker

PLG, also known as protamine phosphate, is a protein that is found in the blood of red blood cells. It is a key component of hemoglobin, which is the protein that makes up the oxygen-carrying portion of red blood cells. PLG has been identified as a potential drug target and has been shown to have a number of potential therapeutic benefits.

One of the key properties of PLG is its ability to interact with certain molecules, such as drugs that are currently being used to treat heart failure. This ability to interact with drugs could make PLG an attractive target for researchers and doctors looking for new treatments for heart failure.

Another potential use for PLG is its role in the regulation of blood pressure. Many studies have shown that PLG levels are regulated in response to changes in blood pressure, and that alterations in PLG levels can have a significant impact on blood pressure. This suggests that PLG could be a useful indicator of blood pressure and could be used as a target for drugs that are currently being used to treat hypertension.

In addition to its potential therapeutic uses, PLG has also been shown to have a number of potential biomarker applications. For example, PLG has been used as a marker for monitoring the effectiveness of different treatments for heart failure, and has been shown to be a reliable predictor of mortality in patients with heart failure.

Overall, PLG is a protein that has a number of potential applications as a drug target and biomarker. Further research is needed to fully understand its properties and potential uses.

Protein Name: Plasminogen

Functions: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells

The "PLG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3