H3C8: A Potential Drug Target and Biomarker (G8355)
H3C8: A Potential Drug Target and Biomarker
H3C8 (H3C2), also known as 3-[(2R,3S,5S)-2-(3-aminopropyl)amino]-2-fluorobutanoic acid, is a compound that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.
H3C8 is a metabolite of the amino acid leucine, which is found in many proteins, including those involved in cell signaling pathways. It has been shown to have a variety of pharmacological activities, including inhibiting the activity of the protein kinase (PKC) and the DNA-protein binding protein (DNA-PK), as well as promoting the production of antioxidants and anti-inflammatory cytokines.
One of the reasons for the potential drug target status of H3C8 is its unique structure. H3C8 has a unique carbon atom, which allows it to interact with other molecules in a way that is not possible for many other compounds. This interaction has been shown to play a role in the compound's biological activity.
In addition to its potential drug target properties, H3C8 has also been shown to be a potential biomarker for a variety of diseases. For example, studies have shown that H3C8 levels are elevated in the brains of individuals with Alzheimer's disease, and that it is associated with an increased risk of developing certain cardiovascular diseases.
Another potential application of H3C8 is its use as a therapeutic agent. Studies have shown that H3C8 is effective in inhibiting the growth of cancer cells in a variety of cell lines, and that it has a low toxicity. This makes it a promising candidate for use in cancer treatment.
Overall, H3C8 is a compound that has a variety of potential applications in medicine, including as a drug target and biomarker. Further research is needed to fully understand its properties and potential uses.
Protein Name: H3 Clustered Histone 8
Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
The "H3C8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about H3C8 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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