Pak6-AS1: A Potential Drug Target Or Biomarker (G644809)

Target Name: PAK6-AS1

NCBI ID: G644809

PAK6-AS1

Pak6-AS1: A Potential Drug Target Or Biomarker

Pak6-AS1, also known as PAK6-AS1, is a protein that is expressed in various tissues, including the brain, heart, and kidneys, and is involved in the regulation of cell signaling pathways. It is a putative uncharacterized protein that has been identified using various bioinformatics and biochemical approaches. This protein has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion, and is thus a potential drug target or biomarker.

Pak6-AS1: Structure and Function

The protein Pak6-AS1 is a member of the tyrosine kinase family and has a molecular weight of approximately 110 kDa. It consists of a 215 amino acid residue protein that contains several unique features, including a long N-terminus, a single transmembrane segment, and a complex cytoplasmic region.

The N-terminus of Pak6-AS1 contains a unique feature that is composed of a variable region and a constant region. The variable region includes several conserved domains, including a putative N-endonuclease domain, a potential tyrosine kinase domain, and a variable region that contains several un conserved amino acids. The constant region includes a unique domain that is involved in the regulation of cell signaling pathways, including the GTPase-activating protein (GAP) signaling pathway.

The cytoplasmic region of Pak6-AS1 is characterized by the presence of several unique features, including a long terminal region that is involved in the regulation of cell adhesion and migration, and a region that is involved in the regulation of cell invasion and metastasis.

Pak6-AS1: Putative Functions

Pak6-AS1 has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion.

First, Pak6-AS1 is involved in the regulation of cell adhesion. It has been shown to play a role in the regulation of tight junction formation and cell-cell adhesion, and to interact with several cytoskeleton proteins, including tubulin (MAPK/ ERK) and spinal gray matter glial-axonal glial synapses (GBP). Through these interactions, Pak6-AS1 can regulate cell membrane tension and influence cell behavior, including endocytosis and cell adhesion.

Second, Pak6-AS1 is involved in cell migration and invasion. It has been shown to play a role in the regulation of cell migration and the invasive properties of cancer cells, by regulating the activity of several cytoskeleton proteins, including tubulin (MAPK) /ERK) and histones (H3K9me3). Through these interactions, Pak6-AS1 can regulate the remodeling of the cytoskeleton, affecting cell migration and aggressive behavior.

Third, Pak6-AS1 is involved in the regulation of cell signaling pathways. It has been shown to play a role in the regulation of several signaling pathways, including the GTPase-activating protein (GAP) signaling pathway. Through these interactions, Pak6- AS1 can regulate the concentration and balance of intracellular signaling molecules and affect cell behavior, including cell proliferation, apoptosis, etc.

Conclusion

Pak6-AS1 is a putative uncharacterized protein that has been identified using various bioinformatics and biochemical approaches. It is a member of the tyrosine kinase family and has several unique features, including a long N-terminus, a single transmembrane segment, and a complex cytoplasmic region. Pak6-AS1 has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion, and is thus a potential drug target or biomarker. Further studies are needed to fully understand the functions of Pak6-AS1 and its potential as a drug.

Protein Name: PAK6 Antisense RNA 1

The "PAK6-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PAK6-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets