Target Name: PAK6
NCBI ID: G56924
Review Report on PAK6 Target / Biomarker Content of Review Report on PAK6 Target / Biomarker
PAK6
Other Name(s): p21(CDKN1A)-activated kinase 6 | PAK-6 | PAK6_HUMAN | PAK5 | PAK-5 | Serine/threonine-protein kinase PAK 6 | PAK6 variant 1 | p21 (RAC1) activated kinase 6 | P21 (RAC1) activated kinase 6, transcript variant 1 | p21-activated protein kinase 6 | p21 protein (Cdc42/Rac)-activated kinase 6 | p21-activated kinase 6 | Serine/threonine-protein kinase PAK 6 (isoform 1)

Pak6: A Potential Drug Target for Cancer

Pak6 (p21(CDKN1A)-activated kinase 6) is a protein that is expressed in various tissues of the body, including brain, heart, and gastrointestinal tract. It is a key regulator of cell growth and division, and is involved in the development and maintenance of tissues. The discovery of Pak6 as a potential drug target has significant implications for the treatment of various diseases, including cancer.

Pak6 function

Pak6 is a serine/thrombin-activated protein that is involved in the regulation of cell growth and division. It is a kinase that is activated by the presence of serine, thrombin, and other factors. Once activated, Pak6 kinase catalyzes the conversion of thrombin to thrombin-activated dimer, which can then induce the phosphorylation of several target proteins.

Pak6 is involved in the regulation of several cellular processes, including cell growth, differentiation, and the association with signaling pathways. It is a key regulator of the TGF-β pathway, which is involved in the regulation of cell growth and division. Pak6 has been shown to play a role in the regulation of cell cycle progression, and is involved in the transition from the G1 to the S phase of the cell cycle.

Pak6 is also involved in the regulation of cell adhesion and migration. It has been shown to play a role in the regulation of tight junction formation, which is involved in the regulation of the movement of cells along the body's surface. Pak6 has also been shown to play a role in the regulation of cell migration, which is involved in the development of new tissues and organs.

Pak6 is a potential drug target

The identification of Pak6 as a potential drug target has significant implications for the treatment of various diseases, including cancer. Cancer is a disease that is characterized by the rapid and uncontrolled growth of cells, leading to the formation of tumors. The regulation of cell growth and division is critical for the development and maintenance of tissues, and is therefore a key factor in the development and progression of cancer.

Pak6 has been shown to play a role in the regulation of cell growth and division, and is therefore a potential drug target for cancer. Several studies have shown that inhibiting Pak6 activity can lead to the inhibition of cancer cell growth and the inhibition of the formation of tumors.

Pak6 has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die. Cancer cells often undergo apoptosis, which is a normal process that helps to remove damaged or dysfunctional cells from the body. However, in cancer cells, apoptosis can be inhibited, leading to the survival and proliferation of cancer cells.

Pak6 has been shown to play a role in the regulation of cell signaling pathways. It is involved in the regulation of several signaling pathways, including the TGF-β pathway, which is involved in the regulation of cell growth and division. The TGF-β pathway is a key regulator of cell growth and development, and is therefore a key target for drugs that are designed to inhibit cell signaling.

Conclusion

Pak6 is a protein that is involved in the regulation of cell growth and division, and is therefore a potential drug target for cancer. The discovery of Pak6 as a potential drug target has significant implications for the treatment of various diseases, including cancer. Further research is needed to fully understand the function of Pak6 and its potential as a drug target.

Protein Name: P21 (RAC1) Activated Kinase 6

The "PAK6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PAK6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PAK6-AS1 | PALB2 | PALD1 | PALLD | PALM | PALM2 | PALM2AKAP2 | PALM3 | PALMD | Palmitoyltransferase | PALS1 | PALS2 | PAM | PAM16 | PAMR1 | PAN2 | PAN3 | PAN3-AS1 | Pancreas transcription factor 1 complex | PANDAR | PANK1 | PANK2 | PANK3 | PANK4 | Pantothenate Kinase | PANTR1 | PANX1 | PANX2 | PANX3 | PAOX | PAPLN | PAPOLA | PAPOLA-DT | PAPOLB | PAPOLG | PAPPA | PAPPA-AS1 | PAPPA-AS2 | PAPPA2 | PAPSS1 | PAPSS2 | PAQR3 | PAQR4 | PAQR5 | PAQR6 | PAQR7 | PAQR8 | PAQR9 | PAR Receptor | PAR-3-PAR-6B-PRKCI complex | Parathyroid Hormone Receptors (PTHR) | PARD3 | PARD3B | PARD6A | PARD6B | PARD6G | PARD6G-AS1 | PARG | PARGP1 | PARK7 | PARL | PARM1 | PARM1-AS1 | PARN | PARP1 | PARP10 | PARP11 | PARP12 | PARP14 | PARP15 | PARP16 | PARP2 | PARP3 | PARP4 | PARP6 | PARP8 | PARP9 | PARPBP | PARS2 | PART1 | PARTICL | PARVA | PARVB | PARVG | Parvovirus initiator complex | PASD1 | PASK | Patatin-like phospholipase domain-containing protein | PATE1 | PATE2 | PATE3 | PATE4 | PATJ | PATL1 | PATL2 | PATZ1 | PAUPAR | PAWR | PAX1 | PAX2