Target Name: PANK2
NCBI ID: G80025
Review Report on PANK2 Target / Biomarker Content of Review Report on PANK2 Target / Biomarker
PANK2
Other Name(s): mPanK2 | PANK2_HUMAN | NBIA1 | Pantothenate kinase 2, mitochondrial (isoform 2) | PANK2 variant 1 | Neurodegeneration with brain iron accumulation 1 (Hallervorden-Spatz syndrome) | pantothenate kinase 2 | Hallervorden-Spatz syndrome | Pantothenate kinase 2, transcript variant 7 | PKAN | pantothenate kinase-associated neurodegeneration | C20orf48 | Pantothenic acid kinase 2 | pantothenic acid kinase 2 | HARP | Pantothenate kinase 2, transcript variant 1 | hPanK2 | HSS | PANK2 variant 7 | Pantothenate kinase 2, mitochondrial mature form | iPanK2 | PanK2 | Pantothenate kinase 2, mitochondrial (isoform 1) | Pantothenate kinase 2, mitochondrial intermediate form | Neurodegeneration with brain iron accumulation | Pantothenate kinase 2, mitochondrial

Pank2 as A Drug and Biomarker Target

Pank2 (mPanK2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell survival and proliferation, and is involved in the development and maintenance of tissues. Pank2 has also been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, it is an attractive target for drug development.

Pank2 functions as a transcription factor that regulates the expression of genes in response to various signaling pathways. It is a key regulator of theNotch signaling pathway, which is involved in the development and maintenance of tissues. Pank2 has been shown to play a role in the regulation of stem cell proliferation and differentiation, and is thought to be involved in the development of various tissues, including blood vessels, neurons, and organs.

In addition to its role in cell survival and proliferation, Pank2 is also involved in the regulation of cell-cell interactions and in the development of tissues. It has been shown to play a role in the regulation of angiogenesis, the formation of new blood vessels, and in the development of cancer. It is also involved in the regulation of inflammation, and has been shown to play a role in the development of autoimmune disorders.

Despite the importance of Pank2 in various biological processes, its role in the development and maintenance of tissues is not well understood. As a result, it is an attractive target for drug development, with potential applications in a variety of diseases.

Pank2 as a drug target

Pank2 has been identified as a potential drug target due to its involvement in a number of diseases. Its role in the regulation of cell survival and proliferation makes it a potential target for cancer treatments. Pank2 has been shown to play a role in the regulation of the Notch signaling pathway, and is thought to be involved in the development and maintenance of tissues. As a result, Pank2 may be a useful target for cancer therapies that target this pathway.

Pank2 has also been shown to be involved in the regulation of angiogenesis, the formation of new blood vessels, and in the development of cancer. Its role in these processes makes it a potential target for therapies aimed at treating cardiovascular disease and other conditions that are characterized by the formation of new blood vessels.

In addition to its potential as a cancer and cardiovascular disease treatment, Pank2 may also be a useful target for other diseases. Its role in the regulation of cell-cell interactions and in the development of tissues makes it a potential target for diseases characterized by the regulation of cell-cell interactions, such as neurodegenerative diseases and autoimmune disorders.

Pank2 as a biomarker

Pank2 has also been shown to be involved in the regulation of stem cell proliferation and differentiation, which makes it a potential target for the development of biomarkers for these conditions. Its role in these processes makes it a potential target for the development of biomarkers for stem cell proliferation and differentiation, as well as for the regulation of tissue regeneration.

In addition to its potential as a drug target and biomarker, Pank2 may also be a useful target for research into the regulation of cell-cell interactions and in the development of tissues. Its role in these processes makes it a potential target for the study of the regulation of cell-cell interactions and the development of tissues, as well as for the investigation of the mechanisms that underlie these processes.

Conclusion

Pank2 is a protein that is involved in a number of biological processes that are important for the development and maintenance of tissues. Its role in the regulation of cell survival and proliferation, as well as its involvement in the Notch signaling pathway, make it an attractive target for drug development. Its potential as a cancer and cardiovascular disease treatment, as well as its potential as a biomarker for these conditions, make it an

Protein Name: Pantothenate Kinase 2

Functions: Mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis (PubMed:15659606, PubMed:17825826, PubMed:17242360, PubMed:16272150). Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) (PubMed:30221726)

The "PANK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PANK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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PANK3 | PANK4 | Pantothenate Kinase | PANTR1 | PANX1 | PANX2 | PANX3 | PAOX | PAPLN | PAPOLA | PAPOLA-DT | PAPOLB | PAPOLG | PAPPA | PAPPA-AS1 | PAPPA-AS2 | PAPPA2 | PAPSS1 | PAPSS2 | PAQR3 | PAQR4 | PAQR5 | PAQR6 | PAQR7 | PAQR8 | PAQR9 | PAR Receptor | PAR-3-PAR-6B-PRKCI complex | Parathyroid Hormone Receptors (PTHR) | PARD3 | PARD3B | PARD6A | PARD6B | PARD6G | PARD6G-AS1 | PARG | PARGP1 | PARK7 | PARL | PARM1 | PARM1-AS1 | PARN | PARP1 | PARP10 | PARP11 | PARP12 | PARP14 | PARP15 | PARP16 | PARP2 | PARP3 | PARP4 | PARP6 | PARP8 | PARP9 | PARPBP | PARS2 | PART1 | PARTICL | PARVA | PARVB | PARVG | Parvovirus initiator complex | PASD1 | PASK | Patatin-like phospholipase domain-containing protein | PATE1 | PATE2 | PATE3 | PATE4 | PATJ | PATL1 | PATL2 | PATZ1 | PAUPAR | PAWR | PAX1 | PAX2 | PAX3 | PAX4 | PAX5 | PAX6 | PAX6-AS1 | PAX7 | PAX8 | PAX8-AS1 | PAX9 | PAXBP1 | PAXBP1-AS1 | PAXIP1 | PAXIP1-AS2 | PAXIP1-DT | PAXX | PBDC1 | PBK | PBLD | PBOV1 | PBRM1 | PBX1 | PBX2