Target Name: GPR148
NCBI ID: G344561
Review Report on GPR148 Target / Biomarker Content of Review Report on GPR148 Target / Biomarker
GPR148
Other Name(s): G protein-coupled receptor 148 | PGR6 | BTR | G protein-coupled receptor PGR6 | brain and testis restricted GPCR | G protein-coupled receptor 148 (GPR148) | Brain and testis restricted GPCR | GP148_HUMAN | Probable G-protein coupled receptor 148 | G-protein coupled receptor PGR6

GPR148: A GPCR as A Drug Target and Biomarker

G protein-coupled receptors (GPCRs) are a family of transmembrane proteins that play a crucial role in cellular signaling. GPCRs are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPR148 is a GPCR that is expressed in various tissues and is involved in several physiological processes. In this article, we will discuss GPR148 as a drug target and its potential as a biomarker.

GPR148 is a 148-kDa protein that is expressed in the brain, heart, and pancreas. It is a member of the GPCR family and is involved in the signaling pathway known as the G-protein-coupled receptor (GPCR) signaling pathway. GPCR signaling pathway is a two-step process that involves the interaction between the GPCR protein and its ligand. The first step is the binding of the ligand to the GPCR protein, and the second step is the activation of the protein.

GPR148 is involved in several physiological processes, including neurotransmission, pain perception, and hormone signaling. In the context of neurotransmission, GPR148 is involved in the regulation of neurotransmitter release from neuronal postsynaptic terminal. It is a known mediator of neurotransmitter release and its activation can modulate the release of neurotransmitters such as dopamine, serotonin, and nitric oxide.

GPR148 is also involved in pain perception. Studies have shown that GPR148 is involved in the regulation of pain signaling in the central nervous system (CNS) and that its activation can modulate the release of pain-related neurotransmitters. Additionally, GPR148 is involved in the regulation of hormone signaling, specifically in the regulation of testosterone levels in men.

GPR148 has also been identified as a potential drug target. The GPCR signaling pathway is a common target for drug development and GPR148 is no exception. Several drugs that have been developed to target GPCRs have been shown to have therapeutic effects, including inhibitors of GPR117, a GPCR that is involved in pain signaling, and agonists of GPR148, which can modulate the activity of GPCRs. Additionally, GPR148 has been shown to be a potential biomarker for several diseases, including neurodegenerative diseases, pain disorders, and psychiatric disorders.

In conclusion, GPR148 is a GPCR that is involved in several physiological processes, including neurotransmission, pain perception, and hormone signaling. Its activation can modulate the release of neurotransmitters and its activation has been shown to be involved in the regulation of several physiological processes. As a result, GPR148 is a potential drug target and a biomarker for several diseases. Further research is needed to fully understand the role of GPR148 in the regulation of physiological processes and its potential as a drug.

Protein Name: G Protein-coupled Receptor 148

Functions: Orphan receptor

The "GPR148 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR148 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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