KRTAP5-3: A Potential Drug Target and Biomarker (G387266)

Target Name: KRTAP5-3

NCBI ID: G387266

KRTAP5-3

KRTAP5-3: A Potential Drug Target and Biomarker

Keratin-associated protein 5-9 (KRTAP5-3) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function make it an attractive target for researchers to study and develop new treatments.

The protein KRTAP5-3 is a member of the Keratin superfamily. It is a protein composed of 96 amino acids with a conserved amino acid sequence and conserved secondary structure. KRTAP5-3 plays an important role in cell proliferation, differentiation and regulation of cell cycle.

In recent years, researchers have found that KRTAP5-3 is up-regulated in a variety of diseases, such as neurodegenerative diseases, cancer and autoimmune diseases. In addition, KRTAP5-3 is also related to the therapeutic effect of certain drugs. Therefore, KRTAP5-3 is considered a potential drug target with good research value and application prospects.

Drug targets refer to molecules that can specifically bind to a certain molecule and cause biological effects, including biological molecules such as proteins, nucleic acids, and polysaccharides. Drug target research is one of the important areas of drug research and development. By studying drug targets, we can better understand the mechanisms of disease and provide targets and ideas for developing new drugs.

KRTAP5-3 is a protein, so it could be a drug target. At the same time, because KRTAP5-3 is up-regulated in a variety of diseases, it can also be used as a potential biomarker. Biomarkers refer to molecules or cells that can reflect disease status, such as tumor markers, inflammatory factors, etc. By detecting and analyzing these biomolecules, we can better understand the patient's disease status and provide a basis for disease diagnosis and treatment.

KRTAP5-3's role in drug research and development doesn't stop there. Because KRTAP5-3 has a conserved amino acid sequence and secondary structure, it can be used as a universal probe to study the functions and interactions of other proteins. In addition, the expression level of KRTAP5-3 may be closely related to the occurrence and development of certain diseases, and therefore can be used as an important biological indicator to monitor disease progression and treatment effects.

In summary, KRTAP5-3 is a protein with significant research value and application prospects. In-depth study of the function and mechanism of KRTAP5-3 can provide important theoretical basis and experimental support for the development of new drugs and treatment options.

Protein Name: Keratin Associated Protein 5-3

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP5-3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP5-3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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