GOLPH3L: A Potential Drug Target and Biomarker for Cancer (G55204)
GOLPH3L: A Potential Drug Target and Biomarker for Cancer
GOLPH3L (Guanosine-triphosphate gene 3-like) is a gene that encodes a protein known as GTK-尾, which is a key regulator of cell growth and differentiation. GTPase-activating protein (GAP) is a family of proteins that transmits signals from the cytoplasm to the nucleus by regulating the activity of transcription factors. GOLPH3L is a member of the GAP family and is expressed in a wide range of tissues and cells.
The GOLPH3L gene was identified as a potential drug target in the context of cancer, specifically brain tumors. Brain tumors are a leading cause of death and disability in the developed world, and there is a significant need for new treatments that can effectively target these tumors. GOLPH3L has been shown to be highly expressed in a variety of brain tumors, including neuroblastoma, astrocytoma, and glioblastoma.
In addition to its potential as a drug target, GOLPH3L has also been shown to be a valuable biomarker for brain tumors. The GOLPH3L gene has been used to generate antibodies that can detect GOLPH3L protein in brain tumors, which could be used as a diagnostic tool or as a target for cancer therapies. The use of antibodies to detect GOLPH3L protein in brain tumors has the potential to revolutionize the field of neuro-oncology, as it allows doctors to more accurately and specifically target tumors that express GOLPH3L.
GOLPH3L has also been shown to play a role in cell signaling and signaling pathways that are important for cancer development. For example, GOLPH3L has been shown to be involved in the regulation of theNotch signaling pathway, a pathway that is important for the development and maintenance of neural stem cells. In addition, GOLPH3L has been shown to be involved in the regulation of the TGF-β signaling pathway, a pathway that is important for cell growth and differentiation.
GOLPH3L has also been shown to be involved in the regulation of cellular processes that are important for cancer progression. For example, GOLPH3L has been shown to be involved in the regulation of cell migration, a process that is important for the development of tumors. In addition, GOLPH3L has been shown to be involved in the regulation of cell invasion and metastasis, which are processes that are important for the development of tumors.
In conclusion, GOLPH3L is a gene that has the potential to be a drug target or a biomarker for a variety of diseases, including cancer. The regulation of cell growth and differentiation by GOLPH3L is an important area of research, and the use of antibodies to detect and target GOLPH3L in cancer cells has the potential to revolutionize the field of neuro-oncology. Further research is needed to fully understand the role of GOLPH3L in cancer development and progression.
Protein Name: Golgi Phosphoprotein 3 Like
Functions: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane
The "GOLPH3L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GOLPH3L comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GOLT1A | GOLT1B | GON4L | GON7 | GOPC | GORAB | GORASP1 | GORASP2 | GOSR1 | GOSR2 | GOT1 | GOT1-DT | GOT1L1 | GOT2 | GOT2P1 | GP1BA | GP1BB | GP2 | GP5 | GP6 | GP9 | GPA33 | GPAA1 | GPALPP1 | GPAM | GPANK1 | GPAT2 | GPAT3 | GPAT4 | GPATCH1 | GPATCH11 | GPATCH2 | GPATCH2L | GPATCH3 | GPATCH4 | GPATCH8 | GPBAR1 | GPBP1 | GPBP1L1 | GPC1 | GPC1-AS1 | GPC2 | GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161
