GOLGA5: Scaffold Protein and Potential Drug Target (G9950)

Target Name: GOLGA5

NCBI ID: G9950

GOLGA5

GOLGA5: Scaffold Protein and Potential Drug Target

GOLGA5 (Golgi-associated protein 5) is a protein that is expressed in various cell types, including neurons and cancer cells. It is a scaffold protein that helps to maintain the integrity of the endoplasmic reticulum (ER), which is the network of tubes and vesicles that carry proteins from the cell body to the cell membrane. GOLGA5 is also known for its role in cell proliferation, and for this reason, it has potential as a drug target or biomarker.

GOLGA5 is a 21-kDa protein that is expressed in the cytoplasm of various cell types. It is composed of a 146 amino acid chain that contains a N-terminus, a transmembrane segment, and a C-terminus. The N-terminus of GOLGA5 contains a putative N-endopeptide that is involved in the formation of the protein. The C-terminus of GOLGA5 contains a putative C-endopeptide that is involved in the formation of the protein.

GOLGA5 is involved in various cellular processes, including cell signaling, cell adhesion, and cell proliferation. One of the well-documented functions of GOLGA5 is its role in cell proliferation. GOLGA5 has been shown to promote the growth and survival of various cell types, including cancer cells.

In addition to its role in cell proliferation, GOLGA5 is also involved in the regulation of cell adhesion. GOLGA5 has been shown to interact with various adhesion molecules, including cadherins and immunoglobulin adhesion molecules. This interaction between GOLGA5 and adhesion molecules may play a role in the regulation of cell-cell adhesion, which is important for various cellular processes, including tissue repair and regeneration.

GOLGA5 is also involved in the regulation of various signaling pathways. GOLGA5 has been shown to interact with various signaling molecules, including TGF-β, Wnt, and Hedgehog. This interaction between GOLGA5 and signaling molecules may play a role in the regulation of cellular processes, including cell proliferation and differentiation.

GOLGA5 has also been shown to be involved in the regulation of cellular transport. GOLGA5 has been shown to interact with various transport proteins, including the protein Transmembrane protein (TMP). This interaction between GOLGA5 and TMP may play a role in the regulation of cellular transport, including the transport of proteins from the endoplasmic reticulum to the cell membrane.

GOLGA5 is also involved in the regulation of cellular signaling pathways that are involved in cell death and stress. GOLGA5 has been shown to interact with various signaling molecules, including Bcl-2 and p53. This interaction between GOLGA5 and Bcl-2 and p53 may play a role in the regulation of cellular processes that are involved in cell death and stress.

GOLGA5 has also been shown to be involved in the regulation of cellular signaling pathways that are involved in cell cycle progression. GOLGA5 has been shown to interact with various signaling molecules, including cyclin D1 and p21. This interaction between GOLGA5 and cyclin D1 and p21 may play a role in the regulation of cellular processes that are involved in cell cycle progression.

In conclusion, GOLGA5 is a protein that is involved in various cellular processes, including cell proliferation, adhesion, and signaling pathways. Its role in these processes makes it a potential drug target or biomarker. Further research is needed to fully understand the function of GOLGA5 and its potential as a drug or biomarker.

Protein Name: Golgin A5

Functions: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport

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