Golgin A8: Role in Cell Signaling and Adhesion (G643699)

Target Name: GOLGA8N

NCBI ID: G643699

GOLGA8N

Other Name(s): Golgin A8 family member N | GOLGA8R | golgin A8 family member N | GOG8N_HUMAN | Golgin subfamily A member 8N

Golgin A8: Role in Cell Signaling and Adhesion

The Golgi system is a complex network of vesicles and folds that forms the Golgi complex in eukaryotic cells. It is a vital part of the endoplasmic reticulum and is involved in the delivery and processing of proteins. The Golgi complex has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the proteins that is associated with the Golgi complex is Golgin A8 (Golgin A8 family member N). Golgin A8 is a protein that is expressed in most tissues of the body and is a member of the Golgi complex. It is characterized by its unique structure, which consists of a long amino acid sequence that is rich in glutamic acid and Asp.

Golgin A8 has been shown to be involved in various cellular processes, including cell signaling, cell adhesion, and cell migration. It is also involved in the regulation of various cellular processes, including cell cycle progression, apoptosis, and inflammation.

One of the key functions of Golgin A8 is its role in cell signaling. Golgin A8 has been shown to be involved in the regulation of various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival. Golgin A8 has been shown to play a key role in the regulation of TGF-β signaling by promoting the stability of the complex between the transcription factor TGF-β and its receptor.

Another function of Golgin A8 is its role in cell adhesion. Golgin A8 has been shown to be involved in the regulation of cell adhesion by promoting the formation of tight junctions anddesmosomes. These structures are responsible for maintaining the integrity of the cell membrane and are essential for the proper functioning of the cell. Golgin A8 has been shown to play a key role in the regulation of tight junction formation by promoting the production ofdesmosome-associated protein (DAP), a protein that is involved in the formation of tight junctions.

Golgin A8 is also involved in the regulation of cell migration. Golgin A8 has been shown to be involved in the regulation of cell migration by promoting the production of the protein N-cadherin. N-cadherin is a transmembrane protein that is involved in cell-cell adhesion and is essential for the proper functioning of the cell. Golgin A8 has been shown to play a key role in the regulation of N-cadherin expression by promoting the production of its downstream target, the protein PIK3CA.

In addition to its role in cell signaling, Golgin A8 is also involved in the regulation of various cellular processes, including cell cycle progression, apoptosis, and inflammation. Golgin A8 has been shown to play a key role in the regulation of cell cycle progression by promoting the production of the protein p21(rdc1). p21(rdc1) is a tumor suppressor protein that is involved in the regulation of cell cycle progression and is often deleted in cancer cells. Golgin A8 has been shown to promote the production of p21(rdc1) by inhibiting the activity of the protein kinase A-TG1.

Golgin A8 is also involved in the regulation of apoptosis. Golgin A8 has been shown to play a key role in the regulation of apoptosis by promoting the production of the protein B-cell lymphotransmitter 1 (BLT1). BLT1 is a protein that is involved in the regulation of apoptosis and is often deleted in cancer cells. Golgin A8 has been shown to promote the production of BLT1 by inhibiting the activity of the protein

Protein Name: Golgin A8 Family Member N

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