Target Name: GOPC
NCBI ID: G57120
Review Report on GOPC Target / Biomarker Content of Review Report on GOPC Target / Biomarker
GOPC
Other Name(s): GOPC_HUMAN | PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10 | fused in glioblastoma | Golgi associated PDZ and coiled-coil motif containing protein | golgi associated PDZ and coiled-coil motif containing | GOPC variant 1 | CAL | FIG | golgi-associated PDZ and coiled-coil motif containing protein | dJ94G16.2 PIST | CFTR-associated ligand | Golgi-associated PDZ and coiled-coil motif-containing protein | Fused in glioblastoma | GOPC1 | Golgi-associated PDZ and coiled-coil motif-containing protein (isoform a) | dJ94G16.2 | PDZ protein interacting specifically with TC10 | Golgi associated PDZ and coiled-coil motif containing, transcript variant 1 | PIST

GPOC: A Potential Drug Target for Various Diseases

The protein known as GPOC (GPOC-HUMAN) has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.GPOC is a transmembrane protein that is expressed in many different tissues and cells in the body. It is a key regulator of the cell cycle and has been shown to play a role in the development and progression of various diseases.

One of the key functions of GPOC is its role in the regulation of the cell cycle. During the cell cycle, GPOC helps to control the movement of chromosomes along the DNA double helix and ensures that the cell divided into two daughter cells at the end of the cycle. This process is crucial for the growth, development, and reproduction of all living organisms.

In addition to its role in cell division, GPOC is also involved in the regulation of cell signaling pathways. It has been shown to play a role in the signaling pathways that regulate cell growth, differentiation, and survival.

One of the ways that GPOC is linked to cancer is its role in the regulation of the angiogenic switch. This is the process by which a cell turns from a normal cell into a cancer cell, and GPOC has been shown to play a key role in this process.

GPOC has also been shown to be involved in the regulation of neurodegenerative disorders. This is the group of diseases that include Alzheimer's disease, Parkinson's disease, and other forms of dementia.

In addition to its role in neurodegenerative disorders, GPOC is also involved in the regulation of autoimmune diseases. This is a group of diseases in which the body's immune system attacks the body's own tissues, including the brain.

GPOC has also been shown to be involved in the regulation of stem cell biology. This is the process by which stem cells develop into fully developed cells, and GPOC has been shown to play a role in this process.

In conclusion, GPOC is a protein that is involved in a wide range of processes in the body, including cell division, signaling pathways, angiogenesis, neurodegenerative disorders, and autoimmune diseases. As a potential drug target or biomarker, GPOC is a promising target for the development of new treatments for a wide range of diseases. Further research is needed to fully understand the role of GPOC in the regulation of the body's various processes and to develop effective treatments.

Protein Name: Golgi Associated PDZ And Coiled-coil Motif Containing

Functions: Plays a role in intracellular protein trafficking and degradation (PubMed:11707463, PubMed:14570915, PubMed:15358775). May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels (By similarity). May also regulate the intracellular trafficking of the ADR1B receptor (PubMed:15358775). May play a role in autophagy (By similarity). Together with MARCHF2 mediates the ubiquitination and lysosomal degradation of CFTR (PubMed:23818989). Overexpression results in CFTR intracellular retention and lysosomaldegradation in the lysosomes (PubMed:11707463, PubMed:14570915)

The "GOPC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GOPC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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