Target Name: GOLIM4
NCBI ID: G27333
Review Report on GOLIM4 Target / Biomarker Content of Review Report on GOLIM4 Target / Biomarker
GOLIM4
Other Name(s): golgi phosphoprotein 4 | Golgi integral membrane protein 4, transcript variant 1 | golgi integral membrane protein, cis | Type II Golgi membrane protein | Golgi phosphoprotein 4 | golgi phosphoprotein of 130 kDa | GOLI4_HUMAN | Golgi integral membrane protein 4 | golgi integral membrane protein 4 | cis Golgi-localized calcium-binding protein | Cis Golgi-localized calcium-binding protein | Golgi integral membrane protein 4 (isoform 1) | GIMPc | 130 kDa golgi-localized phosphoprotein | Golgi integral membrane protein, cis | Golgi phosphoprotein of 130 kDa | type II Golgi membrane protein | Golgi-localized phosphoprotein of 130 kDa | GOLIM4 variant 1 | P138 | Golgi phosphoprotein 4 (GOLPH4) | golgi-localized phosphoprotein of 130 kDa | GOLPH4 | GIMPC | GPP130

GOLIM4: A Potential Drug Target and Biomarker for Glioblastoma

Glioblastoma multiforme (GBM) is one of the most aggressive forms of brain cancer, with a high mortality rate and a poor prognosis. Despite advances in surgical and radiation treatments, the survival rate for GBM patients remains poor, and the disease is often associated with poor quality of life and recurrence.

Golgi phosphoprotein 4 (GOLIM4) is a protein that is expressed in various tissues, including the brain. It is a member of the Golgi complex, which is a network of organelles that play a key role in the proper functioning of cells. GOLIM4 has been shown to be involved in a number of cellular processes, including cell signaling, migration, and invasion.

Recent studies have suggested that GOLIM4 may be a potential drug target for GBM. GOLIM4 has been shown to be overexpressed in GBM tissues, and inhibition of its expression has been shown to have anti-tumor effects. Additionally, GOLIM4 has been shown to interact with several other proteins that are involved in the development and progression of GBM, including the oncogene PDGF.

Furthermore, GOLIM4 has also been shown to be a potential biomarker for GBM. GOLIM4 has been shown to be expressed in various types of GBM, including classical GBM and oligodendrocyte GBM. Additionally, GOLIM4 has been shown to be associated with poor prognosis in GBM patients, with higher expression of GOLIM4 being associated with poor outcomes.

In conclusion, GOLIM4 is a protein that has been shown to be involved in a number of cellular processes that are involved in the development and progression of GBM. As such, it is a potential drug target for GBM and a potential biomarker for GBM. Further research is needed to fully understand the role of GOLIM4 in GBM and to develop effective treatments for this disease.

Protein Name: Golgi Integral Membrane Protein 4

Functions: Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi

The "GOLIM4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GOLIM4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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