GOLGA8J: A Potential Drug Target and Biomarker (G653073)

Target Name: GOLGA8J

NCBI ID: G653073

GOLGA8J

Other Name(s): Golgin A8 family member J | Golgin subfamily A member 8J | golgin A8 family member J | Golgin subfamily A member 8-like protein 3 | GOG8J_HUMAN

GOLGA8J: A Potential Drug Target and Biomarker

Golgi8 (also known as Golgi-associated protein 8) is a family member of the Golgi complex that is expressed in various tissues and plays a critical role in the regulation of cell-cell and cell-extracellular matrix interactions. The Golgi complex is a network of organelles that functions as a scaffold to maintain the integrity of the cytoskeleton and to mediate various signaling pathways. Golgi8, as its name suggests, is involved in the formation and maintenance of the Golgi structure.

Recent studies have identified GOLGA8J as a potential drug target and biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. GOLGA8J has also been shown to be involved in various signaling pathways, including the TGF-β pathway, which plays a crucial role in the development and maintenance of tissues and organs.

GOLGA8J is a 21-kDa protein that is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract. It is highly conserved across different species, and its sequence is similar to that of other Golgi proteins. Golga8 is composed of a unique N-terminal region that contains a conserved transmembrane domain, a unique C-terminal region that contains a conserved cytoplasmic domain, and a unique N-terminal region that contains a conserved cytoplasmic domain.

Golga8 is involved in the formation and maintenance of the Golgi structure. It is one of the components of the transmembrane domain that is involved in the formation of the Golgi cube, which is the basic unit of the Golgi structure. The transmembrane domain is also involved in the formation of the vesicle that encapsulates the Golgi organelles. Golga8 is also involved in the regulation of the level of cytoplasmic proteins in the Golgi, including the level of GLT-1, which is a key regulator of the TGF-β pathway.

In addition to its role in the Golgi structure, Golga8 is also involved in the regulation of various signaling pathways. It has been shown to be involved in the TGF-β pathway, which plays a crucial role in the development and maintenance of tissues and organs . The TGF-β pathway is a complex signaling pathway that is involved in the regulation of cell proliferation, differentiation, and survival. It is composed of several transcription factors, including SMAD1, SMAD4, and TGF-β1, which are involved in the regulation of various cellular processes.

Golga8 has also been shown to be involved in the regulation of theNotch pathway, which is a critical regulator of stem cell proliferation and differentiation. TheNotch pathway is composed of several transcription factors, including Notch1, Notch2, and Notch3, which are involved in the regulation of various cellular processes, including stem cell self-renewal and differentiation.

In addition to its involvement in the TGF-β and Notch pathways, Golga8 has also been shown to be involved in the regulation of various signaling pathways that are involved in the development and maintenance of tissues and organs. the regulation of the Wnt pathway, which is involved in the regulation of stem cell proliferation and differentiation. The Wnt pathway is composed of several transcription factors, including Wnt1, Wnt3, and Wnt4, which are involved in the regulation of various cellular processes.

Golga8 has also been shown to be involved in the regulation of the Hedgehog pathway, which is involved in the regulation of cell proliferation and survival. The Hedgehog pathway is composed of several transcription factors, including

Protein Name: Golgin A8 Family Member J

The "GOLGA8J Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GOLGA8J comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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