Target Name: WDR44
NCBI ID: G54521
Review Report on WDR44 Target / Biomarker Content of Review Report on WDR44 Target / Biomarker
WDR44
Other Name(s): WDR44 variant 1 | WD repeat-containing protein 44 | Rabphilin-11 | WD repeat domain 44 | SYM-4 | RAB11BP | WDR44_HUMAN | RPH11 | rabphilin-11 | WD repeat domain 44, transcript variant 1 | WD repeat-containing protein 44 (isoform 1)

WDR44: A Potential Drug Target and Biomarker

WDR44 is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. The gene, which encodes a protein known as WDR44, is located on chromosome 6 and has been shown to play a role in the development and progression of various diseases.

One of the key features of WDR44 is its role in the regulation of cell growth and differentiation. The protein encoded by the WDR44 gene is known to be involved in the inhibition of the cell cycle, which is the process by which cells divide and grow. This is important for the development and progression of cancer, as the inhibition of cell division can lead to the formation of cancer cells.

Another key function of WDR44 is its role in the regulation of cell survival. The protein encoded by the WDR44 gene has been shown to be involved in the inhibition of cell apoptosis, which is the process by which cells die as a result of environmental or genetic stress. This is important for the development and progression of diseases, as the inhibition of cell apoptosis can lead to the continuation of cell growth and the formation of new disease.

In addition to its role in cell cycle and apoptosis, WDR44 has also been shown to be involved in the regulation of cell adhesion. The protein encoded by the WDR44 gene is known to be involved in the formation of tight junctions, which are a type of cell adhesion that helps to maintain the integrity of tissues. This is important for the development and progression of diseases, as the disruption of cell adhesion can lead to the formation of new tumors.

Furthermore, WDR44 is also known to be involved in the regulation of inflammation. The protein encoded by the WDR44 gene has been shown to be involved in the regulation of inflammation and the immune response. This is important for the development and progression of diseases, as the regulation of inflammation and the immune response can contribute to the development and progression of diseases.

In conclusion, WDR44 is a gene that has been identified as a potential drug target and biomarker for various diseases. Its role in the regulation of cell cycle, apoptosis, and adhesion, as well as its involvement in the regulation of inflammation, make it an attractive target for drug development. Further research is needed to fully understand the potential of WDR44 as a drug and to identify its potential therapeutic uses.

Protein Name: WD Repeat Domain 44

Functions: Downstream effector for RAB11. May be involved in vesicle recycling (By similarity)

The "WDR44 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR44 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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