PLEKHJ1: A GPCR That Plays A Key Role in Cell Signaling and Regulation

Target Name: PLEKHJ1

NCBI ID: G55111

PLEKHJ1

PLEKHJ1: A GPCR That Plays A Key Role in Cell Signaling and Regulation

PLEKHJ1 (GNRPX) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and gastrointestinal tract. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling.

One of the unique features of PLEKHJ1 is its structure. It is a 19-kDa protein that consists of an extracellular region, a transmembrane segment, and an intracellular segment. The extracellular region consists of a single transmembrane domain that is responsible for PLEKHJ1's interaction with other proteins. The transmembrane segment is also known as the extracellular portion of the protein and is responsible for PLEKHJ1's interaction with the cell surface. The intracellular segment is the portion of the protein that enters the cell and is involved in its intracellular signaling functions.

One of the key functions of PLEKHJ1 is its role in cell signaling. PLEKHJ1 is a GPCR that is involved in a variety of signaling pathways, including the regulation of cell growth, differentiation, and survival. It is part of a family of GPCRs that are known as the RhoA gene family, and it is closely related to the protein RhoA.

PLEKHJ1 is also involved in the regulation of ion channels, which are responsible for the flow of electrical current through the cell membrane. It is a member of the TRPV2 subfamily of ion channels and is expressed in many different tissues throughout the body, including the brain, heart, and gastrointestinal tract.

In addition to its role in cell signaling, PLEKHJ1 is also a potential drug target. Several studies have suggested that PLEKHJ1 may be a useful target for the development of new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and gastrointestinal disorders.

One of the reasons for PLEKHJ1's potential as a drug target is its location in the brain. The brain is a complex and highly specialized organ that is responsible for the majority of the body's cognitive and behavioral functions, and it is home to many different types of neurons that are involved in signaling pathways. As a result, any drug that can modulate the activity of PLEKHJ1 in the brain may have a wide range of potential therapeutic applications.

Another reason for PLEKHJ1's potential as a drug target is its role in the regulation of cell signaling. PLEKHJ1 is involved in a variety of signaling pathways that are important for the growth, differentiation, and survival of many different types of cells. As a result, any drug that can modulate the activity of PLEKHJ1 may be able to affect the behavior of a wide range of cells, including cancer cells, neural cells, and muscle cells.

In addition to its potential as a drug target, PLEKHJ1 is also a promising biomarker for a variety of diseases. Its expression has been detected in a variety of tissues and has been associated with a number of different diseases, including cancer, neurodegenerative diseases, and gastrointestinal disorders. As a result, PLEKHJ1 may be a useful indicator of the severity or progression of these diseases, and may be a useful target for diagnostic tests.

Overall, PLEKHJ1 is a protein that is involved in a variety of signaling pathways and has been associated with a number of different diseases. Its potential as a drug target and as a biomarker makes it an attractive target for research into the development of new treatments for a variety of diseases.

Protein Name: Pleckstrin Homology Domain Containing J1

The "PLEKHJ1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLEKHJ1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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