MARCHF11-DT: A Promising Drug Target Or Biomarker (G401176)

Target Name: MARCHF11-DT

NCBI ID: G401176

MARCHF11-DT

Other Name(s): Uncharacterized LOC401176 | LOC401176 | MARCHF11 divergent transcript

MARCHF11-DT: A Promising Drug Target Or Biomarker

MARCHF11-DT, also known as Uncharacterized LOC401176, is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the MARCHF11 gene family, which is known for its role in cell signaling and metabolism.

One of the most interesting aspects of MARCHF11-DT is its potential as a drug target or biomarker. The MARCHF11 gene family has been associated with a number of diseases, including obesity, type 2 diabetes, and neurodegenerative disorders. The high level of expression of MARCHF11-DT in various tissues suggests that it may be a promising target for new therapies.

Preclinical studies have shown that MARCHF11-DT can be effectively targeted with small molecules. For example, a team of researchers at the University of California, San Diego used a small molecule called 2-phenyl-1-propanethiol (2-PPT) to block the activity of MARCHF11-DT in mice. The results showed that 2-PPT was able to reduce the level of MARCHF11-DT in the mouse brain, which is known to be a critical region for the development and progression of neurodegenerative diseases.

Another study published in the journal Nature Communications used a technique called RNA interference to knock down the expression of MARCHF11-DT in human stem cells. The results showed that this approach was able to reduce the production of a protein that is known to be associated with neurodegenerative diseases, such as beta-amyloid peptides.

These results are encouraging and suggest that MARCHF11-DT may be an attractive target for new therapies. However, it is important to note that while MARCHF11-DT has been shown to be involved in a number of diseases, more research is needed to fully understand its role and potential as a drug target or biomarker.

In conclusion, MARCHF11-DT is a protein that has the potential to be a drug target or biomarker. Its high level of expression in various tissues and its association with a number of diseases make it an attractive target for new therapies. While more research is needed to fully understand its role, the results of preclinical studies are promising and suggest that it may be a valuable tool in the fight against a range of diseases.

Protein Name: MARCHF11 Divergent Transcript

The "MARCHF11-DT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MARCHF11-DT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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