Target Name: MARCHF3
NCBI ID: G115123
Review Report on MARCHF3 Target / Biomarker Content of Review Report on MARCHF3 Target / Biomarker
MARCHF3
Other Name(s): MARCH-III | Membrane associated ring-CH-type finger 3 | MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | RING-type E3 ubiquitin transferase MARCHF3 | Membrane-associated RING finger protein 3 | RNF173 | RING-type E3 ubiquitin transferase MARCH3 | E3 ubiquitin-protein ligase MARCH3 | RING finger protein 173 | membrane associated ring-CH-type finger 3 | membrane-associated RING-CH protein III | Membrane-associated RING-CH protein III | E3 ubiquitin-protein ligase MARCHF3 | MARH3_HUMAN | membrane associated ring finger 3

MARCHF3: A Potential Drug Target and Biomarker

MARCHF3, also known as MID-2, is a protein that is expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract. It is a member of the MID family of transcription factors, which are known for their role in regulating gene expression. One of the most interesting aspects of MARCHF3 is its potential as a drug target and biomarker. In this article, we will explore the biology of MARCHF3 and its potential as a drug target, as well as its potential as a biomarker for various diseases.

The Biology of MARCHF3

MARCHF3 is a 21 kDa protein that is expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract. It is a member of the MID family of transcription factors, which are known for their role in regulating gene expression. The MID family of transcription factors includes several other proteins, including MID-1, MID-3, MID-5, and MID-6, which are also involved in the regulation of gene expression.

One of the most interesting aspects of MARCHF3 is its potential as a drug target. MARCHF3 has been shown to play a role in the regulation of cell proliferation and has been shown to interact with several protein kinases, including Src/FAK and Tecplash. These interactions suggest that MARCHF3 may be a potential drug target for the treatment of various diseases, including cancer.

MARCHF3 has also been shown to play a role in the regulation of gene expression in the brain. Studies have shown that MARCHF3 is expressed in various brain regions and that it is involved in the regulation of the expression of genes that are involved in memory and learning. This suggests that MARCHF3 may be a potential drug target for the treatment of neurodegenerative diseases, such as Alzheimer's disease.

MARCHF3 has also been shown to play a role in the regulation of gene expression in the gastrointestinal tract. Studies have shown that MARCHF3 is expressed in the epithelial cells of the gut and that it is involved in the regulation of the expression of genes that are involved in the development and function of the gut. This suggests that MARCHF3 may be a potential drug target for the treatment of various gastrointestinal diseases, including inflammatory bowel disease and gastrointestinal cancer.

Potential Biomarkers for MARCHF3

MARCHF3 has also been shown to play a role in the regulation of gene expression in various diseases, which suggests that it may be a potential biomarker for these diseases. For example, studies have shown that MARCHF3 is involved in the regulation of the expression of genes that are involved in the development and progression of cancer, and that it may be a potential biomarker for cancer.

In addition, studies have shown that MARCHF3 is involved in the regulation of the expression of genes that are involved in the regulation of inflammation, and that it may be a potential biomarker for inflammatory diseases. For example, studies have shown that MARCHF3 is involved in the regulation of the expression of genes that are involved in the production of pro-inflammatory cytokines, and that it may be a potential biomarker for inflammatory bowel disease and other inflammatory diseases.

MARCHF3 has also been shown to play a role in the regulation of gene expression in the regulation of cell survival, which suggests that it may be a potential biomarker for diseases that are characterized by cell death or survival. For example, studies have shown that MARCHF3 is involved in the regulation of the expression of genes that are involved in the

Protein Name: Membrane Associated Ring-CH-type Finger 3

Functions: E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates

The "MARCHF3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MARCHF3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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