TMEM135: A Potential Drug Target for Disabilities (G65084)

Target Name: TMEM135

NCBI ID: G65084

TMEM135

TMEM135: A Potential Drug Target for Disabilities

TMEM135 (FLJ22104) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and kidneys. It is a member of the transmembrane protein family, which means that it spans the cell membrane and extends into the space between cells.

TMEM135 has been identified as a potential drug target or biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and expression patterns make it an attractive target for researchers to study and develop new treatments.

One of the key features of TMEM135 is its transmembrane properties. This means that it is connected to both the cytoplasm and the cell membrane, and its localization to different tissues and organs suggests that it plays an important role in the regulation of cellular processes that are dependent on both the cytoplasm and the cell membrane.

TMEM135 has been shown to be involved in several cellular processes that are important for maintaining cellular homeostasis. For example, it has been shown to be involved in the regulation of ion and water transport, as well as the maintenance of the cell's shape and structure.

In addition to its role in cellular homeostasis, TMEM135 has also been shown to play a key role in several diseases and conditions. For example, it has been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases.

TMEM135 has also been shown to be involved in the development and progression of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. In these conditions, the immune system attacks the body's own tissues, leading to inflammation and damage.

In addition to its potential role in disease, TMEM135 has also been shown to be a promising biomarker for several diseases. For example, it has been shown to be an effective predictor of disease progression in people with Alzheimer's disease, and it has been used as a diagnostic marker for multiple sclerosis.

TMEM135's transmembrane structure and its involvement in cellular homeostasis make it an attractive target for researchers to study and develop new treatments. With further research, it is possible that TMEM135 will be shown to be a valuable drug or biomarker for the treatment of a wide range of diseases.

Protein Name: Transmembrane Protein 135

Functions: Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization

The "TMEM135 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM135 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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