TMEM132D: A Potential Drug Target for Cell Signaling and Migration

Target Name: TMEM132D

NCBI ID: G121256

TMEM132D

TMEM132D: A Potential Drug Target for Cell Signaling and Migration

TMEM132D (MGC138770) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the transmembrane protein family, which means that it spans the cell membrane and extends into the cytoplasm. TMEM132D is involved in a number of cellular processes that are essential for normal function, including cell signaling, migration, and invasion.

One of the key functions of TMEM132D is its role in cell signaling. It is a negative regulator of the protein T-cell factor (TGF-β), which is a well-known signaling molecule that plays a critical role in the development and maintenance of tissues. TGF-β is involved in the regulation of cell proliferation, differentiation, and survival, and is often aberrantly expressed in a variety of diseases, including cancer.

In addition to its role in cell signaling, TMEM132D is also involved in the regulation of cell migration and invasion. It is a critical regulator of the protein PDGFR-尾, which is involved in the formation of platelet aggregates and plays a role in blood clotting. PDGFR-尾 is often aberrantly expressed in various diseases, including cancer and neurodegenerative disorders.

TMEM132D is also involved in the regulation of cell survival and stress responses. It is a critical regulator of the protein p53, which is involved in the regulation of DNA repair and cell apoptosis. p53 is often aberrantly expressed in various diseases, including cancer and neurodegenerative disorders.

In conclusion, TMEM132D is a protein that is involved in a number of critical cellular processes that are essential for normal function. Its role in cell signaling, migration, and invasion, as well as its involvement in the regulation of cell survival and stress responses, make it an attractive drug target for researchers. Further research is needed to fully understand the mechanisms of TMEM132D and its potential as a drug.

Protein Name: Transmembrane Protein 132D

Functions: May serve as a cell-surface marker for oligodendrocyte differentiation

The "TMEM132D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM132D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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