Target Name: IL22RA2
NCBI ID: G116379
Review Report on IL22RA2 Target / Biomarker Content of Review Report on IL22RA2 Target / Biomarker
IL22RA2
Other Name(s): Interleukin-22 receptor subunit alpha-2 (isoform 1) | I22R2_HUMAN | IL-22R-alpha-2 | Cytokine receptor family type 2, soluble 1 | OTTHUMP00000017282 | Interleukin 22 receptor subunit alpha 2, transcript variant 1 | CRF2X | Cytokine receptor class-II member 10 | interleukin 22 receptor subunit alpha 2 | Interleukin-22 receptor subunit alpha-2 | OTTHUMP00000017283 | interleukin 22-binding protein | IL-22BP | interleukin 22 receptor, alpha 2 | ZCYTOR16 | Cytokine receptor family 2 member 10 | cytokine receptor class-II member 10 | ZcytoR16 | MGC150510 | MGC150509 | IL22RA2 variant 1 | cytokine receptor family type 2, soluble 1 | IL-22 receptor subunit alpha-2 | Interleukin-22-binding protein | Interleukin 22-binding protein | IL-22RA2 | Class II cytokine receptor | CRF2-10 | CRF2-S1 | IL22BP | OTTHUMP00000017284

IL-22R?: Exploring a key protein in immune response and inflammation

Interleukin-22 receptor subunit alpha-2 (ISOform 1), also known as IL-22R伪, is a protein that plays a crucial role in the immune response and inflammation. It is a type of cytokine that is produced by various cell types in the body, including T cells, natural killer cells, and macrophages. The IL-22R伪 protein is involved in the signaling process of the cytokine TGF-β, which is a key factor in the regulation of cell growth, differentiation, and inflammation.

IL-22R伪 is a protein that is expressed in various tissues and cells of the body, including the lungs, heart, kidneys, and intestinal tract. It is also expressed in various cell types, including immune cells, nerve cells, and epithelial cells. The IL-22R伪 protein is involved in the regulation of cell growth, differentiation, and survival, and is a potential drug target in the treatment of various diseases.

One of the functions of IL-22R伪 is its role in the regulation of T cell development and function. T cells are a crucial type of immune cell that play a vital role in the regulation of the immune response and the rejection of foreign substances. IL-22R伪 is involved in the signaling process of TGF-β, which is a key factor in the regulation of T cell development and function.

IL-22R伪 is also involved in the regulation of inflammation. When the body is exposed to a foreign substance, such as bacteria, viruses, or cancer cells, IL-22R伪 helps to stimulate the immune response and inflammation. This is important for the elimination of the foreign substance and for the regulation of tissue repair.

Due to its involvement in the regulation of T cell development and function, as well as its role in the regulation of inflammation, IL-22R伪 is a potential drug target for the treatment of various diseases. For example, IL-22R伪 has been shown to be involved in the development and progression of various types of cancer, including lung cancer, breast cancer, and colon cancer. It is also involved in the regulation of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

In addition to its potential use as a drug target, IL-22R伪 is also a potential biomarker for the diagnosis and monitoring of various diseases. For example, the level of IL-22R伪 has been shown to be elevated in the blood and urine of individuals with cancer, and may be a useful biomarker for the diagnosis and monitoring of cancer.

IL-22R伪 is also involved in the regulation of cellular signaling pathways that are important for the regulation of cell growth, differentiation, and survival. This is important for the regulation of cellular processes that are critical for the development and maintenance of tissues and organs.

Overall, IL-22R伪 is a protein that plays a crucial role in the immune response and inflammation. It is a potential drug target and a potential biomarker for the diagnosis and monitoring of various diseases. Further research is needed to fully understand the role of IL-22R伪 in the regulation of cellular processes and its potential as a drug and biomarker.

Protein Name: Interleukin 22 Receptor Subunit Alpha 2

Functions: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses

The "IL22RA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IL22RA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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