IL4R: A Potential Drug Target and Biomarker (G3566)

Target Name: IL4R

NCBI ID: G3566

IL4R

IL4R: A Potential Drug Target and Biomarker

IL4R (Interleukin-4 receptor) is a protein that is expressed in various tissues throughout the body, including the immune system, skin, and hair. It is a member of the interleukin-4 receptor subfamily, which is a family of cytokine receptors that play a crucial role in the regulation of immune and inflammatory responses. IL4R is also known as IL4R nirs variant 1, and it is a single-chain transmembrane protein that consists of an extracellular domain, a transmembrane domain, and an intracellular domain.

IL4R is involved in the regulation of various cellular processes in the immune system, including the regulation of T cell development and function, the regulation of inflammation, and the regulation of cell survival. It is also involved in the regulation of skin and hair growth, and it is thought to play a role in the regulation of skin aging.

IL4R is a potential drug target because of its involvement in the regulation of immune and inflammatory responses. It is also a good candidate for a biomarker because of its ability to be easily measured and its potential to predict the outcome of certain diseases.

One of the main functions of IL4R is its role in the regulation of T cell development and function. T cells are a type of immune cell that play a crucial role in the regulation of immune responses and are involved in the development of many diseases, including cancer. IL4R is involved in the regulation of T cell development and function by promoting the survival and proliferation of T cells, and by regulating their activation and deactivation.

IL4R is also involved in the regulation of inflammation. It is thought to play a role in the regulation of inflammation by promoting the recruitment of immune cells to the site of an infection or inflammation, and by regulating the production of pro-inflammatory cytokines. This helps to keep the immune system under control and prevents excessive inflammation that can lead to tissue damage and the development of diseases.

IL4R is also involved in the regulation of cell survival. It is thought to play a role in the regulation of cell survival by promoting the survival of cancer cells and by inhibiting the clearance of dead cells. This helps to promote the growth and survival of cancer cells, and can contribute to the development and progression of cancer.

IL4R is also a good candidate for a biomarker because of its ability to be easily measured and its potential to predict the outcome of certain diseases. For example, it can be used as a biomarker for the diagnosis and prognosis of certain types of cancer, such as breast cancer and lung cancer. It can also be used as a biomarker for the evaluation of the effectiveness of certain treatments, such as chemotherapy and radiation therapy.

In conclusion, IL4R is a protein that is involved in the regulation of various cellular processes in the immune system, including T cell development and function, inflammation, and cell survival. It is a potential drug target and a good candidate for a biomarker due to its involvement in these processes and its ability to be easily measured and predicted. Further research is needed to fully understand the role of IL4R in these processes and to develop effective treatments for certain diseases.

Protein Name: Interleukin 4 Receptor

Functions: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2

The "IL4R Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IL4R comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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