IL3RA: A Potential Drug Target for Cancer and Neurodegenerative Disorders

Target Name: IL3RA

NCBI ID: G3563

IL3RA

IL3RA: A Potential Drug Target for Cancer and Neurodegenerative Disorders

IL3RA (Interleukin 3 Receptor Subunit Alpha) is a protein that is expressed in various tissues throughout the body, including the immune system, tissues, and organs. It plays a crucial role in the regulation of immune responses, and is also involved in the regulation of cell signaling pathways. As a result, IL3RA has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative disorders.

The IL3RA protein is a subunit of the interleukin 3 receptor (IL3R), which is a protein that is involved in the regulation of immune responses and cell signaling pathways. The IL3R is a transmembrane protein that is expressed in various tissues throughout the body, including the immune system, tissues, and organs. It is composed of an extracellular domain, a transmembrane domain, and an intracellular domain.

The IL3R is involved in the regulation of several different signaling pathways, including the T cell signaling pathway, the B cell signaling pathway, and the immune surveillance pathway. The IL3R is also involved in the regulation of cell proliferation, differentiation, and apoptosis.

One of the most well-studied functions of IL3R is its role in the regulation of T cell responses. T cells are a type of immune cell that play a crucial role in the regulation of immune responses and the development of cancer. The IL3R is involved in the regulation of T cell proliferation, differentiation, and selection, and is also involved in the regulation of T cell cytokine production.

The IL3R is also involved in the regulation of B cell responses, including B cell proliferation, differentiation, and selection. The IL3R is also involved in the regulation of B cell cytokine production, and is thought to play a role in the regulation of autoimmune diseases.

The IL3R is also involved in the regulation of immune surveillance, including the regulation of dendritic cell function and the regulation of T cell responses to self-antigens. The IL3R is also involved in the regulation of cell apoptosis, and is thought to play a role in the regulation of neurodegenerative diseases.

In addition to its role in the regulation of immune responses, the IL3R is also involved in the regulation of cell signaling pathways that are not specific to immune responses. For example, the IL3R is involved in the regulation of cell adhesion, migration, and invasion, and is also involved in the regulation of cell proliferation and differentiation.

The IL3R is a potential drug target and biomarker for a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative disorders. Because of its involvement in the regulation of immune responses and cell signaling pathways, the IL3R is a promising target for the development of new drugs for a variety of diseases.

In conclusion, IL3RA is a protein that is involved in the regulation of immune responses and cell signaling pathways. As a result, it has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative disorders. Further research is needed to fully understand the role of the IL3R in the regulation of immune responses and cell signaling pathways, and to develop new drugs that can target the IL3R in the treatment of these diseases.

Protein Name: Interleukin 3 Receptor Subunit Alpha

Functions: Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity)

The "IL3RA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IL3RA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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