NUDT19: A Protein Targeted for Neurodegenerative Diseases (G390916)
NUDT19: A Protein Targeted for Neurodegenerative Diseases
NUDT19 (RP2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the NUDT family of proteins, which are known for their role in regulating DNA damage repair. NUDT19 has been shown to play a key role in the regulation of cellular processes that are important for brain development and function, such as the regulation of neuron growth and the prevention of neurodegenerative diseases.
One of the unique features of NUDT19 is its ability to interact with other proteins that are involved in the regulation of cellular processes that are important for brain development and function. For example, NUDT19 has been shown to interact with the protein heat shock protein (Hsp22), which is involved in the regulation of stress responses and the maintenance of cellular homeostasis.
In addition to its role in the regulation of cellular processes, NUDT19 has also been shown to play a key role in the development and progression of neurodegenerative diseases. For example, studies have shown that NUDT19 is overexpressed in the brains of individuals with Alzheimer's disease, and that this overexpression is associated with the development of neurodegeneration.
Given the unique role that NUDT19 plays in the regulation of cellular processes and the development and progression of neurodegenerative diseases, it is a promising target for drug development. Researchers are currently working to develop small molecules that can inhibit the activity of NUDT19, with the goal of using these drugs to treat neurodegenerative diseases.
In conclusion, NUDT19 (RP2) is a protein that is expressed in various tissues of the body and plays a key role in the regulation of cellular processes that are important for brain development and function. Its unique ability to interact with other proteins that are involved in the regulation of cellular processes makes it an attractive target for drug development, particularly for the treatment of neurodegenerative diseases.
Protein Name: Nudix Hydrolase 19
Functions: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity). Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity)
The "NUDT19 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUDT19 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
NUDT2 | NUDT21 | NUDT22 | NUDT3 | NUDT4 | NUDT4B | NUDT4P2 | NUDT5 | NUDT6 | NUDT7 | NUDT8 | NUDT9 | NUDT9P1 | NUF2 | NUFIP1 | NUFIP2 | NUGGC | NUMA1 | NUMB | NUMBL | NUP107 | Nup107-160 complex | NUP133 | NUP153 | NUP155 | NUP160 | NUP188 | NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1 | NWD2 | NXF1 | NXF2 | NXF3 | NXF4 | NXF5 | NXN | NXNL1 | NXNL2 | NXPE1 | NXPE2 | NXPE3 | NXPE4 | NXPH1 | NXPH2 | NXPH3 | NXPH4 | NXT1 | NXT2 | NXTAR | NYAP1 | NYAP2 | NYNRIN | NYX | OACYLP | OAF | OARD1 | OAS1 | OAS2 | OAS3 | OASL | OAT | OATP1 | OAZ1
