IL1RAPL2: A Potential Drug Target and Biomarker (G26280)

IL1RAPL2: A Potential Drug Target and Biomarker

Interleukin 1 (IL-1) is a cytokine that plays a crucial role in the regulation of immune and inflammatory responses. The IL-1 receptor, also known as IL-1R, is a protein that is expressed in various tissues throughout the body, including immune cells, endothelial cells, and epithelial cells. The IL-1 receptor is involved in the regulation of immune cell function, cell survival, and inflammation. Interleukin 1 receptor accessory protein like 2 (IL1RAPL2) is a protein that is expressed in various tissues throughout the body, including immune cells, and is known to interact with the IL-1 receptor.

IL1RAPL2 is a protein that is composed of 215 amino acid residues. It has a molecular weight of 23.2 kDa and a pre-cleavage structure of 415 amino acids. IL1RAPL2 is predominantly expressed in the cytoplasm of immune cells, such as T cells, B cells , and macrophages. It is also expressed in the endoplasmic reticulum (ER) and has been shown to be involved in the regulation of immune cell function, including cell survival and proliferation.

One of the key functions of IL1RAPL2 is its interaction with the IL-1 receptor. The IL-1 receptor is a protein that is composed of an extracellular domain, a transmembrane domain, and an intracellular domain. The intracellular domain of the IL-1 receptor is known as the cytoplasmic domain and is involved in the interaction with IL1RAPL2. The cytoplasmic domain of the IL-1 receptor contains a leucine-rich repeat (LRR) domain, which is known to be a critical determinant of the receptor's cytoplasmic localization.

LRR domains are a type of protein domain that is characterized by the presence of a leucine-rich sequence in the protein sequence. LRR domains are often involved in protein-protein interactions and play a crucial role in the regulation of various cellular processes, including cell signaling, protein folding, and stability. The LRR domain of IL1RAPL2 is known to be involved in the interaction with other proteins, including the adapter protein Fyn and the transcription factor NF-kappa-B.

The interaction between IL-1R and IL1RAPL2 is important for the regulation of immune cell function. IL-1R is involved in the regulation of immune cell survival and proliferation, as well as the regulation of cytokine signaling. IL1RAPL2 is thought to play a role in the regulation of these processes by interacting with the IL-1 receptor.

In addition to its interaction with the IL-1 receptor, IL1RAPL2 is also involved in the regulation of cellular processes that are important for immune cell function. For example, IL1RAPL2 is involved in the regulation of the expression and activity of various transcription factors, including NF-kappa-B and transcription factor IL-2. It is also involved in the regulation of cellular signaling pathways, including the JAK/STAT signaling pathway, which is involved in the regulation of immune cell function.

IL1RAPL2 is also involved in the regulation of cellular processes that are important for inflammation. For example, IL1RAPL2 is involved in the regulation of the production and activity of various cytokines, including IL-1, IL-6, and IL-8. These cytokines play a crucial role in the regulation of immune and inflammatory responses. The regulation of

Protein Name: Interleukin 1 Receptor Accessory Protein Like 2

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

IL1RL1 | IL1RL2 | IL1RN | IL2 | IL20 | IL20RA | IL20RB | IL21 | IL21-AS1 | IL21R | IL21R-AS1 | IL22 | IL22RA1 | IL22RA2 | IL23A | IL23R | IL24 | IL25 | IL26 | IL27 | IL27RA | IL2RA | IL2RB | IL2RG | IL3 | IL31 | IL31RA | IL32 | IL33 | IL34 | IL36A | IL36B | IL36G | IL36RN | IL37 | IL3RA | IL4 | IL4I1 | IL4R | IL5 | IL5RA | IL6 | IL6-AS1 | IL6R | IL6R-AS1 | IL6ST | IL6ST-DT | IL6STP1 | IL7 | IL7R | IL9 | IL9R | IL9RP3 | IL9RP4 | ILDR1 | ILDR2 | ILF2 | ILF3 | ILF3-DT | ILK | ILKAP | ILRUN | ILVBL | Imidazoline I2 receptor (I2) | Imidazoline I3 receptor (I3) | Imidazoline receptor | IMMP1L | IMMP2L | IMMT | IMMTP1 | Immunoglobulin A | Immunoglobulin E (IgE) | Immunoglobulin G | Immunoglobulin M | Immunoglobulin-Like Domain Containing Receptor | Immunoproteasome | IMP3 | IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT