IL21R-AS1: A Potential Drug Target and Biomarker (G283888)

Target Name: IL21R-AS1

NCBI ID: G283888

IL21R-AS1

Other Name(s): IL21R antisense RNA 1 | AC002303.5

IL21R-AS1: A Potential Drug Target and Biomarker

The immune system is a crucial part of our body, and it plays a vital role in protecting us from infection and disease. One of the key components of the immune system is natural killer cells, which are responsible for destroying cancer cells and other infected or abnormal cells. IL21R-AS1, an RNA molecule of the IL21R family, plays an important role in the immune system and may become a drug target or biomarker.

IL21R-AS1 is an RNA molecule produced by the IL21R gene. The IL21R gene is located on human chromosome 1p36.1 and is a member of the IL21R family of genes. The IL21R family includes three genes: IL21R1, IL21R2 and IL21R3. The RNA molecules encoded by these three genes can stimulate natural killer cells (NK cells) to produce cytokines, thus exerting an immune regulatory effect. IL21R-AS1 is the only RNA molecule encoded in the IL21R family.

The expression level of IL21R-AS1 can be affected by multiple factors, including immune response, cell cycle, cytokines, growth factors and DNA damage. Studies have shown that the expression level of IL21R-AS1 can control immune responses by regulating multiple signaling pathways. For example, IL21R-AS1 can promote immune cells to inhibit tumor growth through the PD-L1 signaling pathway, and stimulate NK cells to kill tumor cells through the IL-6 signaling pathway. In addition, IL21R-AS1 can also control immune responses by regulating the proportion of T cell subsets.

In addition to its role in the immune system, IL21R-AS1 may also play important roles in other areas. Research shows that IL21R-AS1 can interfere with the development and function of the nervous system. For example, IL21R-AS1 can regulate the distribution of extraneuronal synapses in presynaptic neurons, thereby affecting the connections between neurons. In addition, IL21R-AS1 can also regulate the function of NK cells in the brain, thereby maintaining immune homeostasis in the nervous system.

In drug research, IL21R-AS1 is widely used as a drug target. For example, IL21R-AS1 has been used to treat a variety of tumors, including breast cancer, lung cancer, and lymphoma. Research shows that IL21R-AS1 is a potential drug target that can suppress the excessive response of the immune system and thereby improve the survival rate and quality of life of cancer patients.

In addition, IL21R-AS1 can also be detected as a biomarker. Studies have shown that the expression level of IL21R-AS1 can be used to predict the survival rate of patients with various tumors, including breast cancer, lung cancer, and lymphoma. In addition, IL21R-AS1 can also be used to evaluate the effectiveness of immunotherapy, thereby providing more effective treatment options for tumor patients.

In conclusion, IL21R-AS1 is an RNA molecule that plays an important role in the immune system and nervous system. By regulating multiple signaling pathways, IL21R-AS1 can affect the function of the immune system, thus having an important impact on human health. Therefore, IL21R-AS1 is a potential drug target or biomarker worthy of further study.

Protein Name: IL21R Antisense RNA 1

The "IL21R-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IL21R-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets