IL-1Rrp2: A Potential Drug Target and Biomarker (G8808)
IL-1Rrp2: A Potential Drug Target and Biomarker
The immune system is a critical component of the body that protects it from pathogens and diseases. The immune response is led by a group of specialized immune cells called T-cells, which are responsible for recognizing and destroying foreign substances like viruses and bacteria. However , sometimes the immune system becomes imbalanced and leads to chronic diseases. One of the most common examples of this is autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis. These diseases cause significant discomfort and disability in the affected joints and can also have significant long-term effects on the body.
One of the key proteins involved in the immune response is the interleukin-1 receptor (IL-1 receptor), which is a protein that is expressed in many different types of cells in the body. The IL-1 receptor plays a crucial role in the regulation of the immune response and is involved in the development of autoimmune diseases.
One of the subtypes of the IL-1 receptor is IL-1 receptor regulatory protein 2 (IL-1Rrp2). IL-1Rrp2 is a protein that is expressed in many different types of cells in the body, including immune cells, neurons, and epithelial cells. It is involved in the regulation of the immune response and has been implicated in the development of autoimmune diseases.
IL-1Rrp2 functions by interacting with the IL-1 receptor. The IL-1 receptor is a protein that is expressed in many different types of cells in the body and plays a crucial role in the immune response. It is involved in the regulation of inflammation, differentiation, and survival of immune cells. The IL-1 receptor is composed of two subunits, the IL-1 receptor alpha chain and the IL-1 receptor beta chain.
The IL-1 receptor is involved in the regulation of many different processes in the body, including the regulation of inflammation, differentiation, and survival of immune cells. It is also involved in the regulation of pain and tissue repair. The IL-1 receptor is a transmembrane protein that is located in the cytoplasm of many different types of cells in the body. It is composed of two subunits, the IL-1 receptor alpha chain and the IL-1 receptor beta chain.
The IL-1 receptor is involved in the regulation of many different processes in the body, including the regulation of inflammation, differentiation, and survival of immune cells. It is also involved in the regulation of pain and tissue repair. The IL-1 receptor is a transmembrane protein that is located in the cytoplasm of many different types of cells in the body. It is composed of two subunits, the IL-1 receptor alpha chain and the IL-1 receptor beta chain.
Research has suggested that IL-1Rrp2 may be a drug target for the treatment of autoimmune diseases. Several studies have shown that inhibiting the activity of IL-1Rrp2 can protect against the development of autoimmune diseases in animal models. For example, one study published in the journal Nature Medicine found that inhibiting the activity of IL-1Rrp2 using a small molecule inhibitor protected against the development of rheumatoid arthritis in animal models.
In addition to its potential as a drug target, IL-1Rrp2 has also been identified as a potential biomarker for the diagnosis and monitoring of autoimmune diseases. The IL-1 receptor is involved in the regulation of many different processes in the body, including the regulation of inflammation, differentiation, and survival of immune cells. As such, changes in the activity of the IL-1 receptor may be an indicator of the presence of autoimmune diseases.
Research has suggested that IL-1Rrp2 may be a drug target for the treatment of autoimmune diseases. Several studies have shown that inhibiting the activity of IL-1Rrp2 can protect against the development of autoimmune diseases in animal models. For example, one study published in the journal Nature Medicine found that inhibiting the activity of IL-1Rrp2 using a small molecule inhibitor protected against the development of rheumatoid arthritis in animal models.
In addition to its potential as a drug target, IL-1Rrp2 has also been identified as a potential biomarker for the diagnosis and monitoring of autoimmune diseases. The IL-1 receptor is involved in the regulation of many different processes in the body, including the regulation of inflammation, differentiation, and survival of immune cells. As such, changes in the activity of the IL-1 receptor may be an indicator of the presence of autoimmune diseases.
While further research is needed to fully understand the role of IL-1Rrp2 in the development of autoimmune diseases, its potential as a drug target and biomarker is an exciting area of 鈥嬧?媠tudy. Further research is needed to determine the exact mechanisms by which IL-1Rrp2 Contributes to the development of autoimmune diseases and to develop safe and effective treatments.
Overall, IL-1Rrp2 is a protein that is involved in the regulation of the immune response and has been implicated in the development of autoimmune diseases. While further research is needed to fully understand its role, its potential as a drug target and biomarker is an exciting area of 鈥嬧?媠tudy. Further research is needed to determine the exact mechanisms by which IL-1Rrp2 contributes to the development of autoimmune diseases and to develop safe and effective treatments.
Protein Name: Interleukin 1 Receptor Like 2
Functions: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway
The "IL1RL2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IL1RL2 comprehensively, including but not limited to:
• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
• disease relevance;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
IL1RN | IL2 | IL20 | IL20RA | IL20RB | IL21 | IL21-AS1 | IL21R | IL21R-AS1 | IL22 | IL22RA1 | IL22RA2 | IL23A | IL23R | IL24 | IL25 | IL26 | IL27 | IL27RA | IL2RA | IL2RB | IL2RG | IL3 | IL31 | IL31RA | IL32 | IL33 | IL34 | IL36A | IL36B | IL36G | IL36RN | IL37 | IL3RA | IL4 | IL4I1 | IL4R | IL5 | IL5RA | IL6 | IL6-AS1 | IL6R | IL6R-AS1 | IL6ST | IL6ST-DT | IL6STP1 | IL7 | IL7R | IL9 | IL9R | IL9RP3 | IL9RP4 | ILDR1 | ILDR2 | ILF2 | ILF3 | ILF3-DT | ILK | ILKAP | ILRUN | ILVBL | Imidazoline I2 receptor (I2) | Imidazoline I3 receptor (I3) | Imidazoline receptor | IMMP1L | IMMP2L | IMMT | IMMTP1 | Immunoglobulin A | Immunoglobulin E (IgE) | Immunoglobulin G | Immunoglobulin M | Immunoglobulin-Like Domain Containing Receptor | Immunoproteasome | IMP3 | IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4
