GSTT1 Gene and Its Functions (G2952)

Target Name: GSTT1

NCBI ID: G2952

GSTT1

GSTT1 Gene and Its Functions

GSTT1 (GST class-theta), also known as GSTP2, is a gene that encodes a protein involved in the detoxification of xenobiotics, such as pesticides and polychlorinated biphenyls (PCBs). several transduced genes, such as GSTP1 and GSTP3. The proteins encoded by these genes play important biologically active roles in organisms, including the metabolism and degradation of toxic compounds in the liver.

The protein encoded by the GSTT1 gene is a transducing gene of the GST (gene transfer protein) family. GST is a transmembrane protein whose main function is to transport harmful compounds to the liver and other biological organs for metabolism and degradation. The protein encoded by the GSTT1 gene is a GST isoform, also known as GSTP2. The GSTP2 protein is encoded by the GSTT1 gene and plays an important biological activity in organisms.

The function of the GSTT1 gene is related to many drugs and pollutants. Many pesticides and PCBs are toxic compounds that humans are exposed to in the environment. The liver is one of the most important metabolic organs in the human body, responsible for breaking down and eliminating many harmful compounds. The protein encoded by the GSTT1 gene plays an important role in the liver and is involved in the metabolism and degradation of harmful compounds in the organism.

Variations in the GSTT1 gene are associated with certain diseases. Variations in the GSTT1 gene have been associated with many diseases, such as liver disease and neurological disease, as well as exposure to environmental pollutants. Studies have found that variations in the GSTT1 gene are associated with an increased risk of liver disease and neurological disease. In addition, variations in the GSTT1 gene may also be associated with pesticide exposure, as pesticides are a major risk factor for liver disease.

Knockdown of the GSTT1 gene is associated with drug resistance. Many drugs are highly effective in treating tumors and chronic diseases, but they can also lead to the development of drug resistance. Knockdown of the GSTT1 gene is associated with drug resistance because the GSTT1 protein plays an important role in drug metabolism in the liver. Studies have found that GSTT1 gene knockdown is associated with an increased risk of drug resistance in tumors and chronic diseases.

Overexpression of the GSTT1 gene is associated with certain diseases. Overexpression of the GSTT1 gene is associated with many diseases, such as liver disease and neurological disease, as well as exposure to environmental pollutants. In addition, overexpression of the GSTT1 gene may also be related to tumorigenesis, because the GSTT1 protein plays an important tumorigenic role in the liver.

Interactions with the GSTT1 gene are relevant to drug discovery and development. The GSTT1 protein plays an important role in drug metabolism in the liver. Therefore, studying the interaction of the GSTT1 gene is of great significance for discovering new drugs and treatment strategies. In addition, studying the interaction of GSTT1 genes may also help to develop new biomarkers for predicting drug efficacy and drug resistance.

The GSTT1 gene has broad prospects for clinical application. The GSTT1 protein plays an important role in drug metabolism in the liver. Therefore, studying the interaction of the GSTT1 gene is of great significance for discovering new drugs and treatment strategies. In addition, studying the interaction of GSTT1 genes may also help to develop new biomarkers for predicting drug efficacy and drug resistance.

Protein Name: Glutathione S-transferase Theta 1

Functions: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide

The "GSTT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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