KRTAP5-14P: A Potential Drug Target and Biomarker (G387276)

Target Name: KRTAP5-14P

NCBI ID: G387276

KRTAP5-14P

Other Name(s): KRTAP5-12 | KRTAP5.P2 | keratin associated protein 5-14, pseudogene | KRTAP5P2 | Keratin associated protein 5-14, pseudogene

KRTAP5-14P: A Potential Drug Target and Biomarker

Kaltura - Kaltura

KRTAP5-14P is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the KRTAS family, which includes proteins that are involved in the regulation of mitochondrial function and energy metabolism.

The KRTAP5-14P protein has been identified as a potential drug target due to its involvement in the regulation of cellular processes that are associated with a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

KRTAP5-14P functions as a negative regulator of the mitochondrial inner mitochondrial membrane potential, which is the region of the mitochondrial membrane that is responsible for generating the proton gradient that is used to generate ATP energy.

In cancer, KRTAP5-14P has been shown to play a role in the regulation of mitochondrial function, which can contribute to the development and progression of cancer. For example, studies have shown that KRTAP5-14P is expressed in various types of cancer, including Breast, ovarian, and colorectal cancers.

In addition to its role in cancer, KRTAP5-14P has also been shown to be involved in the regulation of neurodegenerative diseases. For example, studies have shown that KRTAP5-14P is expressed in the brains of individuals with Alzheimer's disease, and that it is involved in the regulation of neurotransmitter synthesis and release.

KRTAP5-14P has also been shown to be involved in the regulation of cardiovascular disease. For example, studies have shown that KRTAP5-14P is expressed in the hearts of individuals with hypertension, and that it is involved in the regulation of contractility and cardiac output.

Due to its involvement in these various processes, KRTAP5-14P has potential as a drug target for a variety of diseases. For example, studies have shown that inhibiting KRTAP5-14P activity can lead to therapeutic effects in cancer, neurodegenerative diseases, and cardiovascular disease.

In addition to its potential as a drug target, KRTAP5-14P has also been identified as a potential biomarker for a variety of diseases. For example, studies have shown that KRTAP5-14P is expressed in various types of cancer, including breast, ovarian, and colorectal cancers.

In addition to its expression in cancer, KRTAP5-14P has also been shown to be expressed in other types of disease, including neurodegenerative diseases and cardiovascular disease. For example, studies have shown that KRTAP5-14P is expressed in the brains of individuals with Alzheimer's disease, and that it is involved in the regulation of neurotransmitter synthesis and release.

In conclusion, KRTAP5-14P is a protein that is involved in the regulation of various cellular processes that are important for the development and progression of cancer, neurodegenerative diseases, and cardiovascular disease. As a result, it has potential as a drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of KRTAP5-14P in these processes and to develop effective treatments.

Protein Name: Keratin Associated Protein 5-14, Pseudogene

The "KRTAP5-14P Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP5-14P comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets