KRTAP5-11: A Potential Drug Target and Biomarker (G440051)

Target Name: KRTAP5-11

NCBI ID: G440051

KRTAP5-11

KRTAP5-11: A Potential Drug Target and Biomarker

Keratin associated protein 5-5 (KRTAP5-11) is a protein that is expressed in various tissues, including hair, nails, and skin. Its function is not well understood, but it has been shown to play a role in the development and maintenance of these tissues. Based on these properties, KRTAP5-11 has potential as a drug target or biomarker.

The search for new treatments for various diseases has led to the development of small molecules that can modulate the expression of genes associated with those diseases. One approach to identifying potential drug targets is to use a database of gene expression data to identify proteins that are over-expressed or under-expressed in response to the disease. The KRTAP5-11 protein is well-suited for this approach due to its broad and consistent expression across various tissues.

KRTAP5-11 has been shown to be involved in several cellular processes that are important for tissue development and maintenance. For example, it has been shown to be involved in the regulation of cell growth, differentiation, and the assembly of tissues. Additionally, KRTAP5-11 has been shown to play a role in the development of diseases such as cancer, neurodegenerative diseases, and autoimmune diseases.

One potential mechanism by which KRTAP5-11 may contribute to the development of these diseases is by participating in the regulation of signaling pathways that promote cell growth and survival. For example, KRTAP5-11 has been shown to be involved in the regulation of the TGF-β pathway, a well-established regulator of cell growth and differentiation.

In addition to its potential role in disease, KRTAP5-11 also has potential as a biomarker. The consistency of its expression across various tissues makes it a promising candidate for use as a diagnostic biomarker for diseases such as cancer, neurodegenerative diseases, and autoimmune diseases. Additionally, the fact that KRTAP5-11 is well-suited for small molecule inhibition makes it a promising target for drug development.

In conclusion, KRTAP5-11 is a protein that has broad and consistent expression across various tissues and has been shown to play a role in several cellular processes that are important for tissue development and maintenance. Its potential as a drug target or biomarker makes it a promising target for further research in the fields of cancer, neurodegenerative diseases, and autoimmune diseases. Further studies are needed to fully understand its function and potential as a drug and biomarker.

Protein Name: Keratin Associated Protein 5-11

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP5-11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP5-11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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