Target Name: NDUFS8
NCBI ID: G4728
Review Report on NDUFS8 Target / Biomarker Content of Review Report on NDUFS8 Target / Biomarker
NDUFS8
Other Name(s): Complex I-23kD | CI-23kD | complex I-23kD | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | TYKY | TYKY subunit | MC1DN2 | Complex I 23kDa subunit | NADH-ubiquinone oxidoreductase 23 kDa subunit | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [Precursor] | NDUS8_HUMAN | CI-23k | NADH:ubiquinone oxidoreductase core subunit S8 | CI23KD | complex I 23kDa subunit

NDUFS8: A Potential Drug Target and Biomarker

Nadirudin Urosov, D.D.

Non-coding RNAs (ncRNAs) have emerged as a promising area for drug discovery in recent years. These non-functional RNAs are involved in various cellular processes and have been implicated in various diseases, including cancer, neurodegenerative diseases, and developmental disorders. One of the known non-coding RNAs that has recently received significant attention is NDUFS8 (Nadirudin Urosov, D.D.).

NDUFS8 is a non-coding RNA that has been identified in various organisms, including bacteria, yeast, and plants. It is characterized by its ability to bind to specific DNA sequences and its role in the regulation of gene expression. NDUFS8 has been shown to play a crucial role in the regulation of gene expression in various organisms, including humans.

Recent studies have suggested that NDUFS8 may have potential as a drug target and biomarker. First, in cancer, NDUFS8 has been shown to be involved in the regulation of cell growth and survival. Several studies have shown that inhibitors of NDUFS8 have the potential to treat various types of cancer, including breast, lung, and ovarian cancer.

Second, in neurodegenerative diseases, NDUFS8 has been shown to be involved in the regulation of protein synthesis and may play a role in the development of neurodegenerative diseases. Several studies have shown that NDUFS8 is involved in the regulation of the production of proteins involved in neurotransmitter synthesis and neurotransmission.

Third, in developmental disorders, NDUFS8 has been shown to be involved in the regulation of gene expression and may play a role in the development of developmental disorders. Several studies have shown that NDUFS8 is involved in the regulation of gene expression in the development of various developmental disorders, including Down syndrome and Fragile X syndrome.

In conclusion, NDUFS8 is a non-coding RNA that has been shown to play a crucial role in various cellular processes. Its potential as a drug target and biomarker make it an attractive area for further research. Further studies are needed to fully understand the role of NDUFS8 in disease and to develop effective treatments.

Protein Name: NADH:ubiquinone Oxidoreductase Core Subunit S8

Functions: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:22499348). Essential for the catalytic activity and assembly of complex I (PubMed:22499348)

The "NDUFS8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFS8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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NDUFV1 | NDUFV2 | NDUFV2P1 | NDUFV3 | NEAT1 | NEB | NEBL | NECAB1 | NECAB2 | NECAB3 | NECAP1 | NECAP2 | NECTIN1 | NECTIN2 | NECTIN3 | NECTIN3-AS1 | NECTIN4 | NEDD1 | NEDD4 | NEDD4L | NEDD8 | NEDD8-activating enzyme E1 | NEDD8-MDP1 | NEDD9 | NEFH | NEFHP1 | NEFL | NEFM | NEGR1 | NEGR1-IT1 | NEIL1 | NEIL2 | NEIL3 | NEK1 | NEK10 | NEK11 | NEK2 | NEK2-DT | NEK3 | NEK4 | NEK5 | NEK6 | NEK7 | NEK8 | NEK9 | NELF Complex | NELFA | NELFB | NELFCD | NELFE | NELL1 | NELL2 | NEMF | NEMP1 | NEMP2 | NEMP2-DT | NENF | NEO1 | NEPRO | NES | NET1 | NETO1 | NETO1-DT | NETO2 | Netrin receptor | NEU1 | NEU2 | NEU3 | NEU4 | NEURL1 | NEURL1-AS1 | NEURL1B | NEURL2 | NEURL3 | NEURL4 | NEUROD1 | NEUROD2 | NEUROD4 | NEUROD6 | NEUROG1 | NEUROG2 | NEUROG3 | Neuromedin U Receptor | Neuronal acetylcholine receptor alpha2beta2 receptor | Neuronal Acetylcholine Receptor alpha3alpha5beta2 Receptor | Neuropeptide FF Receptor | Neuropeptide Y receptor (NPY-R) | Neurotensin receptor | Neurotrophic Factor | Neurotrophic Tyrosine Kinase Receptor (TRK) | NEXMIF | NEXN | NEXN-AS1 | NF-kappaB (NFkB) | NF1 | NF1P1 | NF1P2 | NF2 | NFAM1 | NFASC