Understanding The Role of Neurofilament Protein in Brain Health and Disease

Target Name: NEFM

NCBI ID: G4741

NEFM

Understanding The Role of Neurofilament Protein in Brain Health and Disease

Neurofilament protein (NEFM) is a protein that is expressed in various tissues of the human body, including the brain. It is a member of the neurofilament family, which is a group of transmembrane proteins that play a critical role in the structure and function of neural circuits. One of the functions of NEFM is to help maintain the integrity of the blood-brain barrier, which is a critical barrier that helps to protect the brain from harmful substances and promote the growth and development of new neurons.

In addition to its role in maintaining the blood-brain barrier, NEFM is also involved in a number of other important processes in the brain. For example, it is involved in the regulation of ion channels, which are important for the flow of electrical signals through the brain. It is also involved in the formation of new neurons, and in the regulation of the growth and differentiation of existing neurons.

As a result of its involvement in these important processes, NEFM has been identified as a potential drug target for a number of neurodegenerative diseases. For example, NEFM has been shown to be involved in the development of Alzheimer's disease, and may also be involved in the development of other neurodegenerative diseases such as Parkinson's disease and Huntington's disease.

In addition to its potential use as a drug target, NEFM is also a potential biomarker for a number of neurodegenerative diseases. For example, research has shown that levels of NEFM are often decreased in the brains of individuals with Alzheimer's disease, and that levels of NEFM may be increased in the brains of individuals with other neurodegenerative diseases. This suggests that NEFM may be a useful biomarker for these diseases, and that it may be able to provide valuable information about the progression of these conditions.

Overall, NEFM is a protein that is critical for the structure and function of the brain, and is involved in a number of important processes that are important for the health and well-being of the brain. As a result, it is a potential drug target and biomarker for a number of neurodegenerative diseases. Further research is needed to fully understand the role of NEFM in these conditions, and to develop effective treatments.

Protein Name: Neurofilament Medium Chain

Functions: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity)

The "NEFM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NEFM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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