NECTIN1: Key Protein for Herpes Virus Entry and Cellular Environment

Target Name: NECTIN1

NCBI ID: G5818

NECTIN1

NECTIN1: Key Protein for Herpes Virus Entry and Cellular Environment

Herpes virus (HV) is a member of the Poxviridae family and is characterized by the presence of a latency period and reactivation of the virus after periods of inactivity. The virus is capable of infecting a wide range of host cells, including human and animal cells , and can cause a range of symptoms depending on the severity of the infection. One of the key factors that enable the virus to cause disease is its ability to invade and replicate inside host cells.

The herpes virus entry mediator C (NECTIN1) is a protein that is expressed in the viral genome and is involved in the process of virus entry. NECTIN1 plays a crucial role in allowing the virus to infect host cells and establish a life cycle within the host . The virus uses NECTIN1 to interact with host cell components and facilitate the entry of the virus into the host cell.

NECTIN1 is a member of the Nectin family, which is characterized by the presence of a nucleotide-binding oligomerization (NBO) domain and a nucleotide-binding oligomerization-like (NBO-like) domain. The Nectin family is a widely conserved family that is found in a variety of organisms, including viruses, bacteria, and eukaryotes. The NBO and NBO-like domains are responsible for the virus-host interactions and for the ability of the viruses to invade and replicate inside host cells.

NECTIN1 plays a key role in the process of herpes virus entry by providing a structural interface between the virus and the host cell. The NBO domain of NECTIN1 is responsible for the interaction between the virus and the host cell nucleotide-binding oligomerization (NBO) domain . This interaction allows the virus to bind to specific host cell nucleotides and to establish a life cycle within the host cell.

In addition to its role in virus-host interactions, NECTIN1 is also involved in the regulation of the host cell cellular environment. The NBO-like domain of NECTIN1 is responsible for the interaction between the virus and the host cell cytoskeleton. This interaction allows the virus to regulate the host cell cytoskeleton and to affect the host cell behavior.

The ability of NECTIN1 to interact with the host cell nucleotide-binding oligomerization (NBO) domain and the cytoskeleton is critical for the success of the herpes virus life cycle. The NBO domain of NECTIN1 is responsible for the interaction between the virus and the host cell NBO domain. This interaction allows the virus to bind to specific host cell nucleotides and to establish a life cycle within the host cell.

The NBO-like domain of NECTIN1 is responsible for the interaction between the virus and the host cell cytoskeleton. This interaction allows the virus to regulate the host cell cytoskeleton and to affect the host cell behavior. The ability of NECTIN1 to interact with the host cell Cytoskeleton is critical for the success of the herpes virus life cycle.

NECTIN1 is also involved in the regulation of the host cell cytoskeleton and in the regulation of the host cell cellular environment. The NBO domain of NECTIN1 is responsible for the interaction between the virus and the host cell cytoskeleton. This interaction allows the virus to regulate the host cell cytoskeleton and to affect the host cell behavior.

In conclusion, NECTIN1 is a key protein that plays a critical role in the process of herpes virus entry and in the regulation of the host cell cellular environment. The NBO and NBO-like domains of NECTIN1 are responsible for the interaction between the virus and the host cell nucleotide-binding oligomerization (NBO) domain and the cytoskeleton, respectively. These domains are critical for the success of the herpes virus life cycle and for the regulation of the host cell behavior. As a result, NECTIN1 is an attractive drug

Protein Name: Nectin Cell Adhesion Molecule 1

Functions: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity

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