NDUFV3: A Potential Drug Target for Unmetabolized Neurotransmitters
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NDUFV3: A Potential Drug Target for Unmetabolized Neurotransmitters
NADH dehydrogenase (ubiquinone) flavoprotein 3 (NDUFV3) is a protein that is expressed in the mitochondria of all living cells. It plays a critical role in the electron transport chain of the mitochondria, which is responsible for generating the energy needed by the cell through a process called cellular respiration. NDUFV3 is a key enzyme in the first step of this process, known as the NADH-dependent part of the electron transport chain.
The NADH-dependent part of the electron transport chain is responsible for converting the NADH that is produced by the cytochrome b6f complex into NAD+, which can then be used to generate ATP through the process of cellular respiration. NDUFV3 is the enzyme that performs this critical function.
In recent years, NDUFV3 has emerged as a potential drug target for a variety of diseases. Its role in the electron transport chain makes it an attractive target for diseases that are characterized by the buildup of unmetabolized neurotransmitters or metabolites, such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.
Additionally, NDUFV3 has also been shown to be a potential biomarker for certain diseases. The buildup of unmetabolized neurotransmitters or metabolites leads to increased expression levels of NDUFV3 in neural cells, which provides important insights into the pathogenesis of these diseases. clues.
NDUFV3 is a protein that is expressed in the mitochondria of all living cells. It plays a critical role in the electron transport chain of the mitochondria, which is responsible for generating the energy needed by the cell through a process called cellular respiration.
The NADH-dependent part of the electron transport chain is responsible for converting the NADH that is produced by the cytochrome b6f complex into NAD+, which can then be used to generate ATP through the process of cellular respiration. NDUFV3 is the enzyme that performs this critical function.
In recent years, NDUFV3 has emerged as a potential drug target for a variety of diseases. Its role in the electron transport chain makes it an attractive target for diseases that are characterized by the buildup of unmetabolized neurotransmitters or metabolites, such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.
Additionally, NDUFV3 has also been shown to be a potential biomarker for certain diseases. The buildup of unmetabolized neurotransmitters or metabolites leads to increased expression levels of NDUFV3 in neural cells, which provides important insights into the pathogenesis of these diseases. clues.
In conclusion, NDUFV3 is a protein that plays a critical role in the electron transport chain of the mitochondria. Its function as an enzyme in the NADH-dependent part of the electron transport chain makes it an attractive target for diseases characterized by the buildup of Metabolized neurotransmitters or metabolites. Additionally, NDUFV3 has also been shown to be a potential biomarker for certain diseases, which provides valuable insights into the mechanisms of these diseases. As research continues to advance, NDUFV3 may prove to be a valuable drug target and a useful biomarker for the diagnosis and treatment of a variety of diseases.
Protein Name: NADH:ubiquinone Oxidoreductase Subunit V3
Functions: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I
The "NDUFV3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFV3 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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