KRTAP4-11: A Potential Drug Target and Biomarker (G653240)

Target Name: KRTAP4-11

NCBI ID: G653240

KRTAP4-11

KRTAP4-11: A Potential Drug Target and Biomarker

Kallikrein-related peptidases (KRTAPs) are a family of transmembrane proteins that belong to the serp family. These proteins are involved in various physiological processes in the body, including blood clotting, inflammation, and tissue repair. KRTAP4-11 is a member of the KRTAP family that has been identified as a potential drug target and biomarker.

The KRTAP4-11 protein

KRTAP4-11 is a 14-kDa protein that is expressed in various tissues and cells in the body. It is mainly localized to the plasma membrane of various cell types, including epithelial, endothelial, and immune cells. KRTAP4-11 is involved in the regulation of cell adhesion, migration, and the formation of tight junctions, which are important events in the development and maintenance of tissues and organs.

In addition to its role in cell biology, KRTAP4-11 has also been shown to be involved in the regulation of inflammation and immune responses. It has been shown to play a role in the regulation of inflammation by suppressing the production of pro-inflammatory cytokines. Furthermore, KRTAP4-11 has also been shown to be involved in the regulation of immune responses by controlling the production of immune cells and modulating their function.

Potential drug target

KRTAP4-11 has been identified as a potential drug target due to its unique structure and its involvement in various physiological processes. The KRTAP4-11 protein is involved in the regulation of cell adhesion, which is a critical process in the development and maintenance of tissues and organs. Therefore, compounds that can modulate cell adhesion and disrupt the regulation of cell adhesion processes may be effective in treating various diseases, including cancer, cardiovascular disease, and autoimmune diseases.

In addition to its role in cell adhesion, KRTAP4-11 is also involved in the regulation of inflammation and immune responses. Therefore, compounds that can modulate these processes may also be effective in treating various diseases. For example, KRTAP4-11 has been shown to play a role in the regulation of inflammation by suppressing the production of pro-inflammatory cytokines. Therefore, compounds that can inhibit the production of these cytokines may be effective in treating inflammatory diseases, including cancer, rheumatoid arthritis, and inflammatory bowel disease.

Biomarker

KRTAP4-11 has also been identified as a potential biomarker for several diseases, including cancer, cardiovascular disease, and autoimmune diseases. The expression of KRTAP4-11 has been shown to be altered in various diseases, including cancer, cardiovascular disease, and autoimmune diseases. Therefore, the levels of KRTAP4-11 have been used as a biomarker to diagnose and monitor these diseases.

Compounds that can modulate KRTAP4-11 expression have been shown to be effective in treating various diseases, including cancer, cardiovascular disease, and autoimmune diseases. For example, compounds that can inhibit the production of pro-inflammatory cytokines, such as TNF-alpha, have been shown to be effective in treating inflammatory diseases, including cancer. Similarly, compounds that can modulate the function of KRTAP4-11, such as those that can enhance its expression or degradation, have also been shown to be effective in treating various diseases.

Conclusion

KRTAP4-11 is a protein that is involved in various physiological processes in the body, including cell adhesion, inflammation, and immune responses. Its unique structure and involvement in these processes make it a potential drug target and biomarker. The regulation of cell

Protein Name: Keratin Associated Protein 4-11

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP4-11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP4-11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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