GPR146: A GPCR Targeted for Drug Development (G115330)
GPR146: A GPCR Targeted for Drug Development
GPR146 (GP146_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and intestines. It is a G protein-coupled receptor (GPCR), which means it is a transmembrane protein that is involved in cellular signaling. GPR146 has been identified as a potential drug target and is the focus of ongoing research in the field of pharmacology.
GPR146 is a member of the GPCR family of proteins, which include over 700 different genes that are involved in cellular signaling. GPCR proteins are involved in a wide range of physiological processes in the body, including sensory perception, neurotransmission, and hormone signaling. GPR146 is specifically involved in the regulation of inflammation and pain.
GPR146 is expressed in various tissues of the human body, including the brain, heart, kidneys, and intestines. It is highly expressed in the brain, where it is involved in the regulation of neural circuits and neurotransmission. GPR146 is also expressed in the heart, where it is involved in the regulation of cardiac function and contractility. In the kidneys, GPR146 is expressed in the regulation of inflammation and fibrosis. In the intestines, GPR146 is involved in the regulation of inflammation and inflammation-related pain.
GPR146 is involved in a wide range of cellular signaling pathways. It is involved in the regulation of neurotransmitter release from neurons, which is involved in the transmission of signals in the nervous system. GPR146 is also involved in the regulation of pain perception, which is the body's response to tissue damage or inflammation. GPR146 is involved in the regulation of inflammation in the brain, which is involved in the immune response to invading organisms.
GPR146 has been identified as a potential drug target due to its involvement in a wide range of cellular signaling pathways. It is thought to be involved in the regulation of neurotransmission, pain perception, and inflammation. GPR146 may be a useful drug target for the treatment of a wide range of diseases, including neurodegenerative disorders, pain conditions, and inflammatory diseases.
In conclusion, GPR146 (GP146_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and intestines. It is a G protein-coupled receptor and is involved in the regulation of inflammation and pain. As a potential drug target, GPR146 is being targeted in research to develop new treatments for a wide range of diseases. Further research is needed to fully understand the role of GPR146 in cellular signaling and its potential as a drug target.
Protein Name: G Protein-coupled Receptor 146
Functions: Orphan receptor
The "GPR146 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR146 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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