Target Name: IGSF5
NCBI ID: G150084
Review Report on IGSF5 Target / Biomarker Content of Review Report on IGSF5 Target / Biomarker
IGSF5
Other Name(s): IGSF5_HUMAN | IgSF5 | GSF5 | Immunoglobulin superfamily member 5 | Immunoglobulin superfamily 5 like | JAM-4 | junctional adhesion molecule 4 | JAM4 | Junctional adhesion molecule 4 | immunoglobulin superfamily 5 like | immunoglobulin superfamily member 5

IGSF5: A Potential Drug Target for Immune Response

IGSF5 (Immunoglobulin Light Chain Fragments 5) are a type of protein that is produced by the immune system. These proteins are made up of a variety of different chains, including the constant region, variable region, and secreted region. IGSF5 is a protein that is expressed in a variety of tissues throughout the body, including the spleen, lymph nodes, and Peyer's patches. It is also expressed in the blood and other body fluids.

IGSF5 has been identified as a potential drug target (or biomarker) due to its involvement in a number of different immune responses. For example, IGSF5 has been shown to play a role in the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. It is also involved in the regulation of inflammation, and has been shown to have anti-inflammatory effects.

Additionally, IGSF5 has also been shown to be involved in the development of cancer. For example, studies have shown that IGSF5 is expressed in a variety of cancer cells, and that it may play a role in the development and progression of these diseases.

Despite these promising findings, more research is needed to fully understand the role of IGSF5 in the immune system and its potential as a drug target.

One way to study the role of IGSF5 is through the use of techniques such as mass spectrometry, which allows researchers to identify and quantify the different chains of IGSF5 in a sample. This can help researchers to understand how the different chains of IGSF5 contribute to its overall structure and function.

Another way to study the role of IGSF5 is through the use of biochemical assays, such as ELISA (Enzyme-Linked Affinity Assay) and western blotting. These assays can be used to measure the levels of IGSF5 in a sample, as well as its specificity and sensitivity to different treatments.

In addition to these techniques, researchers may also use animal models to study the role of IGSF5 in the immune system. For example, they may use mice or cell lines to show that IGSF5 plays a role in the development of autoimmune diseases, or to study its anti-inflammatory effects.

Overall, IGSF5 is a protein that has the potential to be a drug target due to its involvement in a variety of different immune responses. Further research is needed to fully understand its role in the immune system and its potential as a therapeutic agent.

Protein Name: Immunoglobulin Superfamily Member 5

Functions: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity)

The "IGSF5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IGSF5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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