Target Name: IGSF11
NCBI ID: G152404
Review Report on IGSF11 Target / Biomarker Content of Review Report on IGSF11 Target / Biomarker
IGSF11
Other Name(s): OTTHUMP00000215226 | Brain and testis-specific immunoglobulin superfamily protein | cancer/testis antigen 119 | VSIG3 | Bt-IGSF | CT119 | OTTHUMP00000215138 | V-set and immunoglobulin domain containing 3 | brain and testis-specific immunoglobulin superfamily protein | BTIGSF | V-set and immunoglobulin domain-containing protein 3 | Cancer/testis antigen 119 | immunoglobulin superfamily member 11 | MGC35227 | CXADRL1 | OTTHUMP00000215140 | CXADR like 1 | Immunoglobulin superfamily member 11 | Immunoglobulin superfamily member 11 (isoform a) | BT-IgSF | IGS11_HUMAN | IGSF11 variant 1 | Brain and testis-specific immunoglobin superfamily protein | Igsf13 | Immunoglobulin superfamily member 11, transcript variant 2 | OTTHUMP00000215139 | IGSF11 variant 2 | Immunoglobulin superfamily member 11, transcript variant 1 | Immunoglobulin superfamily member 11 (isoform b) | IgSF11 | OTTHUMP00000215225 | brain and testis-specific immunoglobin superfamily protein

IGSF11: A Potential Drug Target for Liver Cancer, Autoimmune Hepatitis and Chronic Hepatitis B

IGSF11 (intrahepatic stem cell factor 11) is a protein that is expressed in the liver and has been shown to play a role in the development and progression of several diseases, including liver cancer. The IGSF11 gene has also been linked to several diseases, including autoimmune hepatitis and chronic hepatitis B.

Recent studies have shown that IGSF11 is a potential drug target for several diseases, including liver cancer, autoimmune hepatitis, and chronic hepatitis B. The exact mechanism of IGSF11's effects on these diseases is not yet fully understood, but it is thought to work by regulating cellular processes that are important for disease progression.

One of the ways that IGSF11 has been shown to contribute to disease progression is by promoting the growth and proliferation of cancer cells. This is thought to happen by inhibiting the activity of several cell signaling pathways, including the TGF-β pathway. This pathway is involved in cell growth, division, and repair, and is often disrupted in cancer cells. By inhibiting the activity of TGF-β, IGSF11 may be able to inhibit the growth and proliferation of cancer cells.

Another way that IGSF11 has been shown to contribute to disease progression is by promoting the development of immune-mediated diseases, such as autoimmune hepatitis. This is thought to happen by interfering with the immune response, which is important for protecting the body against infection and disease.

IGSF11 has also been shown to be involved in the development and progression of chronic hepatitis B, a serious disease that can lead to liver damage and even liver failure. This is thought to happen by contributing to the immune response and the production of certain proteins that can cause inflammation in the liver.

In conclusion, IGSF11 is a protein that has been shown to play a role in several diseases, including liver cancer, autoimmune hepatitis, and chronic hepatitis B. Its exact mechanism of action is not yet fully understood, but it is thought to work by regulating cellular processes that are important for disease progression. As such, IGSF11 may be a valuable drug target for the development of new treatments for these diseases.

Protein Name: Immunoglobulin Superfamily Member 11

Functions: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth

The "IGSF11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IGSF11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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