Target Name: NDUFB8
NCBI ID: G4714
Review Report on NDUFB8 Target / Biomarker Content of Review Report on NDUFB8 Target / Biomarker
NDUFB8
Other Name(s): OTTHUMP00000020833 | NDUB8_HUMAN | complex I ASHI subunit | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | OTTHUMP00000020835 | OTTHUMP00000020836 | NADH:ubiquinone oxidoreductase ASHI subunit | ASHI | NADH-ubiquinone oxidoreductase ASHI subunit | NADH:ubiquinone oxidoreductase subunit B8 | NDUFB8 variant 1 | NADH:ubiquinone oxidoreductase subunit B8, transcript variant 1 | complex I-ASHI | CI-ASHI | Complex I-ASHI | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (isoform 1) | MC1DN32 | Complex I ASHI subunit

NDUFB8 Drug Target: A New Hope for Uterine Cancer Treatment

Native Developmental Uterine Fibroblastoma (NDUFB8) is a relatively rare type of uterine cancer that arises from the fibroblasts that line the uterine lining. It is characterized by the presence of undifferentiated cells in the uterine tissue, as well as the formation of tumors composed of these cells. Despite its relatively rare occurrence, NDUFB8 is considered a potentially aggressive cancer, and its treatment options are limited.

The discovery of NDUFB8 as a potential drug target is significant because it represents a new avenue for the development of effective therapies for this aggressive form of uterine cancer. The identification of a potential drug target allows researchers to focus their efforts on developing small molecules or other compounds that can inhibit the growth and survival of NDUFB8 cells.

One of the key challenges in the treatment of NDUFB8 is the presence of the undifferentiated cells in the uterine tissue. These cells are highly resistant to chemotherapy and other forms of treatment, which makes it difficult to completely remove them. Additionally, the presence of these cells makes it difficult to predict the response of the cancer to any given treatment.

The identification of a potential drug target for NDUFB8 has the potential to revolutionize the treatment of this aggressive form of cancer. By inhibiting the growth and survival of NDUFB8 cells, researchers can potentially slow down or even stop the progression of the disease. This could lead to improved outcomes for patients, including longer overall survival times and a reduction in the risk of recurrence.

The study of NDUFB8 as a potential drug target is still in its early stages, but it is an exciting development in the fight against this aggressive form of uterine cancer. Further research is needed to fully understand the potential of this drug target and to develop effective therapies for the treatment of NDUFB8.

In conclusion, the discovery of NDUFB8 as a potential drug target represents a significant breakthrough in the treatment of this aggressive form of uterine cancer. While further research is needed to fully understand its potential, the identification of a potential target has the potential to lead to the development of effective therapies for this disease.

Protein Name: NADH:ubiquinone Oxidoreductase Subunit B8

Functions: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

The "NDUFB8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFB8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NDUFB9 | NDUFC1 | NDUFC2 | NDUFC2-KCTD14 | NDUFS1 | NDUFS2 | NDUFS3 | NDUFS4 | NDUFS5 | NDUFS6 | NDUFS7 | NDUFS8 | NDUFV1 | NDUFV2 | NDUFV2P1 | NDUFV3 | NEAT1 | NEB | NEBL | NECAB1 | NECAB2 | NECAB3 | NECAP1 | NECAP2 | NECTIN1 | NECTIN2 | NECTIN3 | NECTIN3-AS1 | NECTIN4 | NEDD1 | NEDD4 | NEDD4L | NEDD8 | NEDD8-activating enzyme E1 | NEDD8-MDP1 | NEDD9 | NEFH | NEFHP1 | NEFL | NEFM | NEGR1 | NEGR1-IT1 | NEIL1 | NEIL2 | NEIL3 | NEK1 | NEK10 | NEK11 | NEK2 | NEK2-DT | NEK3 | NEK4 | NEK5 | NEK6 | NEK7 | NEK8 | NEK9 | NELF Complex | NELFA | NELFB | NELFCD | NELFE | NELL1 | NELL2 | NEMF | NEMP1 | NEMP2 | NEMP2-DT | NENF | NEO1 | NEPRO | NES | NET1 | NETO1 | NETO1-DT | NETO2 | Netrin receptor | NEU1 | NEU2 | NEU3 | NEU4 | NEURL1 | NEURL1-AS1 | NEURL1B | NEURL2 | NEURL3 | NEURL4 | NEUROD1 | NEUROD2 | NEUROD4 | NEUROD6 | NEUROG1 | NEUROG2 | NEUROG3 | Neuromedin U Receptor | Neuronal acetylcholine receptor alpha2beta2 receptor | Neuronal Acetylcholine Receptor alpha3alpha5beta2 Receptor | Neuropeptide FF Receptor | Neuropeptide Y receptor (NPY-R) | Neurotensin receptor