Target Name: GPR107
NCBI ID: G57720
Review Report on GPR107 Target / Biomarker Content of Review Report on GPR107 Target / Biomarker
GPR107
Other Name(s): DKFZp667C222 | GP107_HUMAN | GPR107 variant 3 | FLJ22591 | lung seven transmembrane receptor 1 | Protein GPR107 (isoform 3) | G protein-coupled receptor 107 | MGC15440 | RP11-88G17 | Lung seven transmembrane receptor 1 | GCDRP | LUSTR1 | Protein GPR107 | G protein-coupled receptor 107, transcript variant 3 | KIAA1624 | FLJ20998 | bA138E2.2

GPR107: A Potential Drug Target and Biomarker for Diseases

GPR107 (DKFZp667C222) is a G protein-coupled receptor (GPCR) that is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract. It is involved in the regulation of various physiological processes, including insulin secretion, inflammation, and pain perception.

GPR107 has been identified as a potential drug target due to its unique biology and the involvement of several diseases. One of the main reasons for its potential as a drug target is its expression in the brain, which suggests that it may play a role in the development and progression of neurological disorders.

Additionally, GPR107 has been shown to be involved in the regulation of pancreatic insulin secretion, which is critical for maintaining normal blood sugar levels. This suggests that targeting GPR107 may be a promising approach to treat type 1 diabetes.

Another potential mechanism by which GPR107 may be involved in disease is its role in pain perception. GPR107 has been shown to be involved in the regulation of pain signaling in the body, which suggests that it may play a role in the development of chronic pain.

In addition to its potential as a drug target, GPR107 has also been shown to be a potential biomarker for several diseases. For example, GPR107 has been shown to be involved in the regulation of insulin sensitivity in the body, which suggests that it may be a useful biomarker for the development of type 2 diabetes.

GPR107 has also been shown to be involved in the regulation of inflammation in the body, which suggests that it may be a useful biomarker for the development of inflammatory diseases.

In conclusion, GPR107 is a GPCR that has the potential to be a drug target or biomarker for several diseases. Its unique expression in the brain and its involvement in the regulation of insulin secretion, pain perception, and inflammation make it an attractive target for further research. Further studies are needed to fully understand the biology of GPR107 and its potential as a drug or biomarker.

Protein Name: G Protein-coupled Receptor 107

Functions: Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024). Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity)

The "GPR107 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR107 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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