GSTO2: A Drug Target / Disease Biomarker (G119391)

Target Name: GSTO2

NCBI ID: G119391

GSTO2

GSTO2: A Drug Target / Disease Biomarker

GSTO2 (Gastrin-Releasing Subfamily of Transient Activator of secretion (GRS) 2) is a protein that is expressed in various tissues of the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the GRS family, which includes other proteins that are involved in the production of gastrin, a hormone that stimulates the release of digestive enzymes.

GSTO2 is unique because of its ability to interact with the neurotransmitter GABA, which is a chemical that is involved in the regulation of many different cellular processes, including cell signaling and neurotransmission. This interaction between GSTO2 and GABA has important implications for the function of the protein, as GABA is known to play a role in modulating the activity of other proteins, including those involved in the development and progression of cancer.

One of the key functions of GSTO2 is its role in the regulation of gastric acid secretion. Gastric acid is a digestive fluid that is produced by the stomach and is essential for the digestive process. However, too much gastric acid can cause harm, as it can cause ulcers and other problems in the digestive tract. GSTO2 is involved in the regulation of gastric acid secretion by interacting with GABA, which helps to maintain a balance of Gastrin and Gastric acid.

Another important function of GSTO2 is its role in the regulation of insulin secretion. Insulin is a hormone that is produced by the pancreas and is responsible for regulating the levels of glucose (sugar) in the blood. However, too much insulin can cause harm, as it can cause hypoglycemia (low blood sugar). GSTO2 is involved in the regulation of insulin secretion by interacting with GABA, which helps to maintain a balance of insulin and Growth hormone (GH).

GSTO2 is also involved in the regulation of other physiological processes that are important for the body, including cell signaling, neurotransmission, and inflammation. For example, GSTO2 has been shown to be involved in the regulation of pain perception, and it has also been shown to play a role in the regulation of the immune system.

GSTO2 is also a potential drug target (or biomarker) due to its unique interaction with GABA. Studies have shown that GSTO2 is a good candidate for targeting with small molecules, including those that are designed to modulate the activity of GABA receptors. This suggests that GSTO2 may be a useful target for the development of new treatments for a variety of diseases, including cancer, diabetes, and neurological disorders.

GSTO2 is also a potential biomarker for certain diseases, as its levels can be affected by a variety of factors, including the levels of GABA, insulin, and other hormones. For example, GSTO2 levels have been shown to be affected by the levels of stress, alcohol, and certain medications. This suggests that GSTO2 may be a useful biomarker for a variety of diseases, including stress-related disorders, alcohol use disorder, and certain medications.

In conclusion, GSTO2 is a unique protein that is involved in the regulation of several important physiological processes in the body. Its interaction with the neurotransmitter GABA suggests that it may be a useful target for the development of new treatments for a variety of diseases. Further research is needed to fully understand the role of GSTO2 in the regulation of physiological processes, and to determine its potential as a drug target or biomarker.

Protein Name: Glutathione S-transferase Omega 2

Functions: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA)

The "GSTO2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTO2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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