NDUFAF1: A Drug Target and Biomarker for NADH Dehydrogenase Complex I

Target Name: NDUFAF1

NCBI ID: G51103

NDUFAF1

NDUFAF1: A Drug Target and Biomarker for NADH Dehydrogenase Complex I

NADH (nicotinamide adenine dinucleotide) is a crucial coenzyme found in all living cells that plays a pivotal role in energy metabolism. It is a dinucleotide, consisting of two nucleotides joined together, and is involved in the transfer of electrons during processes such as cellular respiration . NAD+ is a central electron carrier in these processes, while NADH is the source of the electrons.

The NADH dehydrogenase (NDUFAF1) complex I is a protein assembly factor that plays a crucial role in the regulation of NADH levels and metabolism. It is composed of multiple subunits, including NDUFAF1, NDUFAF2, NDUFAF3, and NDUFAF4, which are involved in the assembly , function, and localization of NADH.

The NDUFAF1 complex is a protein-protein interaction (PPI) domain and contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for its stability and function. The farnesylated cysteine 鈥嬧?媟esidue is involved in the formation of the NADH dehydrogenase (NDH) complex I and plays a crucial role in its stability and function.

The NDUFAF1 complex is also involved in the regulation of NAD+ levels and metabolism. NADH is a precursor of NAD+, which is a central electron carrier in various cellular processes. The NADH dehydrogenase (NDH) complex I is responsible for converting NADH to NAD+, which is then used in the production of ATP by the cytochrome oxidase (C oxidase).

The NDUFAF1 complex is also involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation. It has been shown to play a role in the regulation of cell cycle progression, apoptosis, and inflammation.

The use of NADH and its precursor NAD+ have been widely investigated as potential drug targets and biomarkers. NAD+ has been shown to have a variety of physiological functions, including the regulation of energy metabolism, DNA replication, and cell growth.

NADH has also been shown to play a role in the regulation of cellular processes such as cell cycle progression, apoptosis, and inflammation. It has been shown to have a variety of physiological functions, including the regulation of energy metabolism, DNA replication, and cell growth.

The NDUFAF1 complex is a protein-protein interaction (PPI) domain and contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for its stability and function. The NDUFAF1 complex is also involved in the regulation of NAD+ levels and metabolism, as well as the regulation of cellular processes such as cell cycle progression, apoptosis, and inflammation.

The use of NADH and its precursor NAD+ have been widely investigated as potential drug targets and biomarkers. NAD+ has been shown to have a variety of physiological functions, including the regulation of energy metabolism, DNA replication, and cell growth.

NADH has also been shown to play a role in the regulation of cellular processes such as cell cycle progression, apoptosis, and inflammation. It has been shown to have a variety of physiological functions, including the regulation of energy metabolism, DNA replication, and cell growth.

The NDUFAF1 complex is a protein-protein interaction (PPI) domain and contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for its stability and function. The NDUFAF1 complex is also involved in the regulation of NAD+ levels and metabolism, as well as the regulation

Protein Name: NADH:ubiquinone Oxidoreductase Complex Assembly Factor 1

Functions: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I

The "NDUFAF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFAF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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