NDUFA4L2: A Potential Drug Target Or Biomarker for Neurological Conditions

Target Name: NDUFA4L2

NCBI ID: G56901

NDUFA4L2

NDUFA4L2: A Potential Drug Target Or Biomarker for Neurological Conditions

NDUFA4L2 (FLJ26118) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the N-linked DUF4 gene family, which is involved in the production of proteins that play a critical role in various cellular processes. One of the functions of NDUFA4L2 is to help regulate the transport of nutrients and oxygen into the brain, which is essential for maintaining healthy brain function.

Recent studies have identified NDUFA4L2 as a potential drug target or biomarker for a variety of neurological and cardiovascular conditions, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. The exact mechanism by which NDUFA4L2 is involved in these conditions is not yet fully understood, but it is known that it plays a role in the regulation of the blood-brain barrier, which is the barrier that separates the brain from the rest of the body and is responsible for controlling the exchange of nutrients, oxygen, and other substances into and out of the brain.

One of the unique features of NDUFA4L2 is its ability to cross the blood-brain barrier and interact with the extracellular matrix (ECM) components, which are responsible for providing structure and support to the brain cells. This ability has led some researchers to consider NDUFA4L2 as a potential therapeutic target for conditions such as Alzheimer's disease, which is characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain.

In addition to its potential therapeutic applications, NDUFA4L2 has also been identified as a potential biomarker for certain neurological conditions. For example, some studies have shown that levels of NDUFA4L2 are elevated in the brains of individuals with Alzheimer's disease, and that these levels are associated with the severity of the disease. Other studies have also shown that NDUFA4L2 is expressed in the brains of individuals with Parkinson's disease, and that these levels are associated with the severity of the disease.

While the exact role of NDUFA4L2 in these conditions is not yet fully understood, it is clear that it plays a critical role in the regulation of brain function. Further research is needed to determine the exact mechanisms by which NDUFA4L2 is involved in these conditions, and to explore its potential as a drug target or biomarker.

Protein Name: NDUFA4 Mitochondrial Complex Associated Like 2

The "NDUFA4L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFA4L2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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