GPC2: A Protein Involved in Various Cellular Processes (G221914)
GPC2: A Protein Involved in Various Cellular Processes
GPC2, or Glypican-2, is a protein that is expressed in various tissues throughout the body. It is a member of the glypican family, which is a group of extracellular matrix (ECM) proteins that are involved in the formation of the ECM and play a role in various cellular processes, including cell signaling, tissue repair, and regeneration.
GPC2 is characterized by its unique structure, which consists of a long amino acid sequence that is repeated multiple times. This repetition is known as a \"dimerization loop\" and is a hallmark of the glypican family. The multiple repeat loops of GPC2 give the protein a highly conserved and stable structure, which allows it to function in a variety of cellular contexts.
GPC2 is involved in many different cellular processes, including cell signaling, adhesion, migration, and invasion. It is a key regulator of cell-cell adhesion, as it helps to maintain the integrity of cell-cell contacts and allows cells to stick together in tissues. GPC2 is also involved in the regulation of cell migration and invasion, as it helps to guide these processes by controlling the distribution of adhesion molecules and other ECM components.
In addition to its role in cell signaling and cell-cell adhesion, GPC2 is also a potential drug target. Its unique structure and multiple functions make it an attractive target for small molecules, antibodies, and other therapeutic agents. GPC2 has also been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
GPC2 has also been shown to play a role in the regulation of stem cell proliferation and differentiation. It is a key regulator of the stem cell marker, PDGFR-尾, which is involved in the maintenance of stem cell stemness. to play a role in the regulation of cell proliferation and apoptosis in various tissues, including the brain, liver, and muscle.
In conclusion, GPC2 is a protein that is involved in a variety of cellular processes throughout the body. Its unique structure and multiple functions make it an attractive target for small molecules, antibodies, and other therapeutic agents. Its role in cell signaling, adhesion, migration, and invasion, as well as its potential as a drug target, make GPC2 a promising target for the development of new treatments for a variety of diseases. Further research is needed to fully understand the role of GPC2 in cellular processes and its potential as a drug target.
Protein Name: Glypican 2
Functions: Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity)
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More Common Targets
GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3
