GPD2 Plays A Crucial Role in Intracellular Signaling Pathway (G2820)
GPD2 Plays A Crucial Role in Intracellular Signaling Pathway
GPD2 (Glycophospholipidase D2) is a protein that is expressed in most tissues of the body and plays a crucial role in the intracellular signaling pathway known as the phosphatidylinositol (PMA) signaling pathway. GPD2 is a key enzyme in the breakdown of phosphatidylcholine (PC), which is a major phospholipid in cell membranes. The breakdown of PC by GPD2 is a critical step in the production of new phospholipids, including inositol and ceramide, which are involved in various cellular processes such as inflammation, metabolism, and signaling.
GPD2 is a 28-kDa protein that consists of 156 amino acids. It is a single-chain protein that contains 10 transmembrane domains and one extracellular domain. The transmembrane domains are responsible for the protein's localization to the endoplasmic reticulum (ER) and for its interactions with various signaling molecules, while the extracellular domain is involved in the protein's interaction with the cell surface.
GPD2 is a well-known protein that has been studied extensively in the context of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. GPD2 has been shown to be involved in the regulation of cellular signaling pathways, including the PMA signaling pathway.
The PMA signaling pathway is a critical pathway that is involved in various cellular processes, including cell signaling, cell division, and cell survival. The pathway is characterized by the production of two key signaling molecules, inositol and ceramide, which are produced from the breakdown of PC. Inositol is a key signaling molecule that is involved in the regulation of various cellular processes, including cell signaling and metabolism. Ceramide is a signaling molecule that is involved in the regulation of inflammation and cellular signaling.
GPD2 is a key enzyme in the breakdown of PC, which is a major phospholipid in cell membranes. The breakdown of PC by GPD2 is a critical step in the production of new phospholipids, including inositol and ceramide.
GPD2 has been shown to be involved in the regulation of the PMA signaling pathway. GPD2 has been shown to activate the PMA signaling pathway by promoting the production of inositol and ceramide. This activation of the pathway is critical for the regulation of various cellular processes, including cell signaling, cell division, and cell survival.
In addition to its role in the PMA signaling pathway, GPD2 has also been shown to be involved in the regulation of other cellular processes. GPD2 has been shown to be involved in the regulation of cell adhesion, as well as in the regulation of cellular signaling pathways that are involved in cell growth, differentiation, and survival.
GPD2 has also been shown to be involved in the regulation of inflammation. GPD2 has been shown to be involved in the regulation of various signaling pathways that are involved in, including the production of pro-inflammatory cytokines and the regulation of the immune response.
GPD2 has also been shown to be involved in the regulation of cellular signaling pathways that are involved in cell metabolism and energy production. GPD2 has also been shown to be involved in the regulation of various cellular signaling pathways that are involved in cell metabolism, including the production of glucose and the regulation of cellular energy production.
GPD2 has also been shown to be involved in the regulation of cellular signaling pathways that are involved in cell signaling and differentiation. GPD2 has also been shown to be involved in the regulation of various cellular signaling pathways that are involved in cell signaling and differentiation, including the regulation of cell proliferation and the regulation of cellular
Protein Name: Glycerol-3-phosphate Dehydrogenase 2
Functions: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device
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More Common Targets
GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A | GPR89B | GPRACR
